Journal
MULTIPLE SCLEROSIS JOURNAL
Volume 20, Issue 12, Pages 1658-1661Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1352458514522103
Keywords
Neuromyelitis optica; aquaporin 4; demyelinating; pain; neuropathic pain; brief pain inventory; SF36; quality of life
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Funding
- Specialist Commissioning Group of the National Health Service (NHS)
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Though pain in neuromyelitis optica (NMO) has been described in two recent reports, the proportion with true neuropathic pain (NP), its features, impact on activities of daily living (ADL) and quality of life has not been well characterised. A cross-sectional study of 50 NMO patients with transverse myelitis was performed using Douleur Neuropathique 4, Brief Pain Inventory, Extended Disability Status Scale and Short Form 36. NP was identified in 62% of patients. Pain was constant in 68% affecting most ADL. Pain was associated with significant reduction of the SF36 Mental Composite Score. The high prevalence of NP and associated disability necessitates an in-depth enquiry in patients with NMO.
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