Towards molecular imaging of multiple sclerosis

Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2)

(2010) Andrew G. Horti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

High field (9.4 Tesla) magnetic resonance imaging of cortical grey matter lesions in multiple sclerosis

(2010) Klaus Schmierer et al.   BRAIN

In vivo imaging of neuroinflammation: a comparative study between [18F]PBR111, [11C]CLINME and [11C]PK11195 in an acute rodent model

(2010) Nadja Van Camp et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation

(2010) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

T1 cortical hypointensities and their association with cognitive disability in multiple sclerosis

(2010) Francesca Bagnato et al.   Multiple Sclerosis Journal

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Emerging role of the cannabinoid receptor CB2 in immune regulation: therapeutic prospects for neuroinflammation

(2009) Guy A. Cabral et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

In Vivo Quantification of Myelin Changes in the Vertebrate Nervous System

(2009) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

A Biomathematical Modeling Approach to Central Nervous System Radioligand Discovery and Development

(2009) Q. Guo et al.   JOURNAL OF NUCLEAR MEDICINE

Quantification of Translocator Protein (18 kDa) in the Human Brain with PET and a Novel Radioligand, 18F-PBR06

(2009) Y. Fujimura et al.   JOURNAL OF NUCLEAR MEDICINE

Initial Evaluation of 11C-DPA-713, a Novel TSPO PET Ligand, in Humans

(2009) C. J. Endres et al.   JOURNAL OF NUCLEAR MEDICINE

Multisequence-imaging protocols to detect cortical lesions of patients with multiple sclerosis: Observations from a post-mortem 3 Tesla imaging study

(2009) Francesca Bagnato et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Imaging outcomes for neuroprotection and repair in multiple sclerosis trials

(2009) Frederik Barkhof et al.   Nature Reviews Neurology

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

(2009) William C. Kreisl et al.   NEUROIMAGE

In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI

(2009) C. Mainero et al.   NEUROLOGY

Synthesis and biological evaluation of carbon-11- and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging

(2009) Nele Evens et al.   NUCLEAR MEDICINE AND BIOLOGY

From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases

(2008) M. Dubois-Dalcq et al.   BRAIN

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

(2008) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Synthesis and Biological Evaluation of Substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the Study of the Peripheral Benzodiazepine Receptor Using Positron Emission Tomography

(2008) Christopher J. R. Fookes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies

(2008) B. Ji et al.   JOURNAL OF NEUROSCIENCE

Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2′-deoxycytidine analog

(2008) Caius G Radu et al.   NATURE MEDICINE

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

(2008) Paul Edison et al.   NEUROBIOLOGY OF DISEASE

The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

(2008) Dean F Wong et al.   NEUROPSYCHOPHARMACOLOGY

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

(2008) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors

(2007) Masao Imaizumi et al.   NEUROIMAGE

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

(2007) Masahiro Fujita et al.   NEUROIMAGE