Dietary DHA amplifies LXA4 circuits in tissues and lymph node PMN and is protective in immune-driven dry eye disease

Goblet Cells Contribute to Ocular Surface Immune Tolerance—Implications for Dry Eye Disease

(2017) Flavia Barbosa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Defining a mechanistic link between pigment epithelium–derived factor, docosahexaenoic acid, and corneal nerve regeneration

(2017) Thang Luong Pham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury

(2017) Izhar Livne-Bar et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of pro-resolving lipid mediators in ocular diseases

(2017) Jessica Wei et al.   MOLECULAR ASPECTS OF MEDICINE

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

The role of systemic and topical fatty acids for dry eye treatment

(2017) Stefano Barabino et al.   PROGRESS IN RETINAL AND EYE RESEARCH

An eye on nutrition: The role of vitamins, essential fatty acids, and antioxidants in age-related macular degeneration, dry eye syndrome, and cataract

(2016) Meagen M. McCusker et al.   CLINICS IN DERMATOLOGY

Specialized proresolving lipid mediators in humans with the metabolic syndrome after n–3 fatty acids and aspirin

(2015) Anne E Barden et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance

(2015) Philip C. Calder   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Female-Specific Downregulation of Tissue Polymorphonuclear Neutrophils Drives Impaired Regulatory T Cell and Amplified Effector T Cell Responses in Autoimmune Dry Eye Disease

(2015) Yuan Gao et al.   JOURNAL OF IMMUNOLOGY

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Potential for daily supplementation of n-3 fatty acids to reverse symptoms of dry eye in mice

(2014) Akiko Harauma et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators

(2013) Brian T. Kalish et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of dietary supplementation with fish oil on dry eye syndrome subjects: randomized controlled trial

(2013) Tetsuya KAWAKITA et al.   BIOMEDICAL RESEARCH-TOKYO

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

(2013) Megan L. Jones et al.   JOURNAL OF LIPID RESEARCH

Dry Eye Disease

(2012) William Stevenson   ARCHIVES OF OPHTHALMOLOGY

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

(2012) Philip C. Calder   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Resolvins D1, D2, and Other Mediators of Self-Limited Resolution of Inflammation in Human Blood following n-3 Fatty Acid Supplementation

(2012) E. Mas et al.   CLINICAL CHEMISTRY

Dietary ω-3 Fatty Acid and Fish Intake and Incident Age-Related Macular Degeneration in Women

(2011) William G. Christen   ARCHIVES OF OPHTHALMOLOGY

Recovery of Corneal Sensitivity, Calcitonin Gene-Related Peptide–Positive Nerves, and Increased Wound Healing Induced by Pigment Epithelial–Derived Factor Plus Docosahexaenoic Acid After Experimental Surgery

(2011) M. Soledad Cortina   ARCHIVES OF OPHTHALMOLOGY

Fat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses

(2011) Sueleyman Bilal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gender differences in re-epithelialisation time in fungal corneal ulcers

(2011) Tiruvengada Krishnan et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Estrogen negatively regulates epithelial wound healing and protective lipid mediator circuits in the cornea

(2011) Samantha B. Wang et al.   FASEB JOURNAL

Docosahexaenoic acid, protectins and dry eye

(2010) Maria S Cortina et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells

(2009) Mark Bouwens et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Endogenous LXA4 Circuits Are Determinants of Pathological Angiogenesis in Response to Chronic Injury

(2009) Alexander J. Leedom et al.   AMERICAN JOURNAL OF PATHOLOGY

Selective Survival Rescue in 15-Lipoxygenase-1-deficient Retinal Pigment Epithelial Cells by the Novel Docosahexaenoic Acid-derived Mediator, Neuroprotectin D1

(2009) Jorgelina M. Calandria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute Changes in Dietary  -3 and  -6 Polyunsaturated Fatty Acids Have a Pronounced Impact on Survival following Ischemic Renal Injury and Formation of Renoprotective Docosahexaenoic Acid-Derived Protectin D1

(2009) I. R. Hassan et al.   JOURNAL OF IMMUNOLOGY

Significance of lipid mediators in corneal injury and repair

(2009) Sachidananda Kenchegowda et al.   JOURNAL OF LIPID RESEARCH

IL-17 disrupts corneal barrier following desiccating stress

(2009) C S De Paiva et al.   Mucosal Immunology

Topical Omega-3 and Omega-6 Fatty Acids for Treatment of Dry Eye

(2008) Saadia Rashid   ARCHIVES OF OPHTHALMOLOGY

Effect of dietary supplementation with increasing doses of docosahexaenoic acid on neutrophil lipid composition and leukotriene production in human healthy volunteers

(2008) Françoise Stanke-Labesque et al.   BRITISH JOURNAL OF NUTRITION

Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease

(2008) Nicolas G. Bazan   JOURNAL OF LIPID RESEARCH

Lipid Autacoids in Inflammation and Injury Responses: A Matter of Privilege

(2008) K. Gronert   MOLECULAR INTERVENTIONS