Article
Microbiology
Andreas Mollebjerg, Lorena Gonzales Palmen, Klaus Gori, Rikke Louise Meyer
Summary: The colonization of textiles by bacteria and subsequent formation of biofilms are influenced by the hydrophobic and hygroscopic properties of the textile material, which suggests that modifying surface properties could direct bacterial behavior in a more favorable direction.
MICROBIOLOGY SPECTRUM
(2021)
Article
Microbiology
Xinli Sun, Jiyu Xie, Daoyue Zheng, Riyan Xia, Wei Wang, Weibing Xun, Qiwei Huang, Ruifu Zhang, Akos T. Kovacs, Zhihui Xu, Qirong Shen
Summary: Microbial interactions play a crucial role in the stability and functionality of microbial communities. This study used co-occurrence network analysis and quantitative PCR to investigate the importance of each species in synthetic biofilm communities. The results showed that metabolic exchanges and resource competition are significant factors in species interactions.
Review
Pharmacology & Pharmacy
Karan Razdan, Jorge Garcia-Lara, V. R. Sinha, Kamalinder K. Singh
Summary: This review focuses on the mechanism of biofilm formation and the role of biofilms in chronic wounds, as well as various formulation strategies and delivery systems used to eradicate or disperse biofilms. The clinical research on the treatment of biofilm-infected chronic wounds is also discussed.
DRUG DISCOVERY TODAY
(2022)
Review
Biochemistry & Molecular Biology
Leszek Blicharz, Lidia Rudnicka, Joanna Czuwara, Anna Waskiel-Burnat, Mohamad Goldust, Malgorzata Olszewska, Zbigniew Samochocki
Summary: Atopic dermatitis is a common inflammatory skin disease caused by epidermal barrier defects leading to immune dysregulation. Recent research has shown that skin microbiota and bacterial biofilms have a negative impact on skin barrier function, contributing to the onset and exacerbation of atopic dermatitis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Cell & Tissue Engineering
Pegah Moharrami Yeganeh, Safa Tahmasebi, Abdolreza Esmaeilzadeh
Summary: Severe traumatic wounds and burns can cause mortality and functional disabilities, and the balance of the skin microenvironment is crucial for the healing process. Tissue engineering approaches can be used to facilitate skin repair and regeneration.
REGENERATIVE MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Yu Chen, Weipeng Lu, Yanchuan Guo, Yuntao Xie, Yi Zhu, Yeping Song
Summary: Combining ROS-scavenging and antibacterial activities, multifunctional gelatin/chitosan composite microspheres effectively alleviate oxidative stress and bacterial invasion in chronic wounds. The gelatin/chitosan scaffold with good biocompatibility promotes cell proliferation.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Medicine, Research & Experimental
Taraj Vyas, Vamshi Krishna Rapalli, Dinesh Kumar Chellappan, Kamal Dua, Sunil Kumar Dubey, Gautam Singhvi
Summary: Biofilms are communities of microbes that are difficult to eradicate and have a significant impact on the skin disorders. With the increasing antibiotic resistance, new treatment methods including nanotherapies have become a focus of attention.
Article
Dermatology
Paulo J. Alves, Ruben T. Barreto, Brigitte M. Barrois, Luc G. Gryson, Sylvie Meaume, Stan J. Monstrey
Summary: Biofilms play a major role in delaying chronic wounds from healing and pose a significant treatment challenge due to their resistance towards antimicrobial agents. However, there is a window of opportunity post-debridement when biofilms are more susceptible to topical antiseptics. Among commonly used antiseptics, PVP-I stands out for its broad spectrum of antimicrobial activity, potent antibiofilm efficacy, lack of acquired resistance, low cytotoxicity, good tolerability, and wound healing promotion.
INTERNATIONAL WOUND JOURNAL
(2021)
Review
Immunology
Dorota Satala, Miriam Gonzalez-Gonzalez, Magdalena Smolarz, Magdalena Surowiec, Kamila Kulig, Ewelina Wronowska, Marcin Zawrotniak, Andrzej Kozik, Maria Rapala-Kozik, Justyna Karkowska-Kuleta
Summary: Periodontal disease is influenced by the presence of microorganisms in the oral cavity, including Candida albicans, which collaborates with bacteria to survive and propagate infection. This article highlights various virulence factors of C. albicans, such as cell surface proteins, secreted proteases, and the dynamic structure of the fungal cell wall. The interactions between C. albicans and bacteria in the formation of biofilms and communication systems are discussed. These virulence factors present new challenges for diagnosis and treatment of periodontal diseases.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Zahra Rajabloo, Mohammad Reza Farahpour, Parvaneh Saffarian, Saeed Jafarirad
Summary: This study synthesized zinc oxide/malachite nanocomposite and its coating form with chitosan and investigated their physicochemical characterization as well as biomedical effects, including antibacterial activity, antioxidant properties, cytotoxicity, modulation in gene expressions, and histopathological parameters. The results showed that the nanocomposites had strong antibacterial activity and antioxidant properties, and the ointments produced from the nanocomposites exhibited wound healing activity. The expressions of IL-1 beta, IL-6, and TNF-alpha decreased while the expressions of IL-10, TGF-beta, and bFGF increased with the administration of the nanocomposite ointments.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Eleonora Secchi, Giovanni Savorana, Alessandra Vitale, Leo Eberl, Roman Stocker, Roberto Rusconi
Summary: It has been found that the mechanical stability of Pseudomonas aeruginosa streamers mainly relies on the presence of extracellular DNA (eDNA) and the exopolysaccharide Pel. Controlling the composition of streamers can effectively control the formation of biofilm structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Jiajun Dong, Luhan Liu, Liying Chen, Yuqiang Xiang, Yabin Wang, Youbao Zhao
Summary: Bacterial biofilms possess distinct community properties that affect various aspects of our daily lives. Multispecies biofilms are undoubtedly the dominant form of biofilms in nature. In this study, we investigate the effect of the coexistence of Enterococcus faecalis, Escherichia coli, and Salmonella enteritidis on triple-species biofilm formation. Our results demonstrate that the coexistence of these three species enhances biofilm biomass and leads to restructuring of the biofilm. Furthermore, the composition of the extracellular matrix and the transcriptomic profile of E. faecalis in response to coexistence are significantly changed compared to mono-species biofilms.
MICROBIOLOGY SPECTRUM
(2023)
Review
Materials Science, Biomaterials
Wenjing Xu, Xin Qing, Shengli Liu, Zhencheng Chen, Yewei Zhang
Summary: This article discusses the applications of manganese dioxide (MnO2) in the detection and treatment of bacterial infections, including various treatment methods and imaging techniques. These studies are of great significance for further exploring the antibacterial applications of MnO2 nanomaterials.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Dermatology
Yulei Jia, Fengchao Chen, Tongtong Yan, Siya Zhang, Mohamed M. Salem, Soumya Singh, Mounir M. Salem-Bekhit, Sanjay Kirshan Kumar, Muhammad Mehr Ali
Summary: The incidence of squamous cell carcinoma (SCC) is increasing, and environmental factors play a crucial role in its onset. This study found significant associations between SCC and various environmental variables, gender, Fitzpatrick skin type, occupation, duration of sun exposure, exposure to carcinogens, dietary practices, history of skin wounds, wound location, duration, size, and depth.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Microbiology
Horia Todor, Nadia Herrera, Carol A. Gross
Summary: DedA family proteins are highly conserved and nearly ubiquitous integral membrane proteins found in archaea, bacteria, and eukaryotes. Recent studies have identified that eukaryotic DedA proteins are phospholipid scramblases, while some bacterial DedA proteins are undecaprenyl phosphate flippases. Our phylogenetic analysis reveals three major DedA subfamilies with distinct functions, including undecaprenyl-phosphate (UndP) flippases and putative phospholipid flippases.
Letter
Surgery
Giuseppe Visconti, Akitatsu Hayashi, Girolamo Tartaglione, Takumi Yamamoto, Alessandro Bianchi, Marzia Salgarello
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2020)
Article
Surgery
Matteo Torresetti, Alessandro Scalise, Giovanni Di Benedetto
Summary: Breast reduction surgery is a common procedure performed by plastic surgeons worldwide. The arrow flap technique, a modification of the vertical scar technique, involves harvesting double lateral glandular and cutaneous flaps to tighten and shape the base of the breast, improving breast projection. Postoperative outcomes showed overall satisfactory results with low complications.
ANNALS OF PLASTIC SURGERY
(2021)
Letter
Surgery
Giuseppe Visconti, Alessandro Bianchi, Marzia Salgarello
Letter
Surgery
Giuseppe Visconti, Alessandro Bianchi, Marzia Salgarello
AESTHETIC PLASTIC SURGERY
(2022)
Article
Surgery
Alessandro Bianchi, Marzia Salgarello, Giuseppe Visconti
Summary: This study presents a novel brachioplasty technique called lipobrachiopexy, which aims to improve cosmetic outcomes through lymph-sparing surgery and tendon suspension suture. The procedure showed good results with high patient and surgeon satisfaction, no major complications, and preserved lymphatic function. The torso-brachial angles also showed significant improvements after the surgery.
AESTHETIC PLASTIC SURGERY
(2022)
Review
Surgery
Matteo Torresetti, Yasmine Zavalloni, Benedetta Peltristo, Giovanni Di Benedetto
Summary: Surgical drains are commonly used in breast augmentation surgery to prevent complications, but their effectiveness is still uncertain.
AESTHETIC PLASTIC SURGERY
(2022)
Article
Surgery
Giuseppe Visconti, Akitatsu Hayashi, Alessandro Bianchi, Girolamo Tartaglione, Roberto Bartoletti, Marzia Salgarello
Summary: Identifying functioning lymphatic vessels preoperatively through ultrasound can improve the efficacy of lymphaticovenular anastomosis. The hand/foot sign in advanced-stage lymphedema patients can serve as a simple clinical indicator for determining the presence of functional lymphatic channels.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Surgery
Giuseppe Visconti, Alessandro Bianchi, Akitatsu Hayashi, Marzia Salgarello
Summary: Ultrasound technology can study the microvascular anatomy of the ALT flap donor site preoperatively, providing a virtual surgical plan for the operating surgeon.
JOURNAL OF RECONSTRUCTIVE MICROSURGERY
(2022)
Article
Surgery
Alessandro Bianchi, Marzia Salgarello, Akitatsu Hayashi, Johnson C-S Yang, Giuseppe Visconti
Summary: The study focused on 232 patients with extremity lymphedema who underwent lymphaticovenular anastomosis (LVA) and found that venule flow dynamics have an independent impact on outcomes, but recipient venules (RV) have been neglected in literature. By evaluating RV, an algorithm was proposed to assist lymphatic microsurgeons in selecting RV for anastomosis configuration.
JOURNAL OF RECONSTRUCTIVE MICROSURGERY
(2022)
Article
Dermatology
Antonio Stanizzi, Matteo Torresetti, Francesca Barbisan, Benedetta Peltristo, Yasmine Zavalloni, Giovanni Di Benedetto
Summary: Nodular cutaneous amyloidosis is the rarest variant of primary localized cutaneous amyloidosis, and management typically involves surgical excision. However, there may be a risk of functional complications in certain locations, and incomplete surgical removal can be successful in some cases.
CASE REPORTS IN DERMATOLOGY
(2021)
Review
Surgery
Matteo Torresetti, Lina Zuccatosta, Giovanni Di Benedetto
Summary: This systematic review evaluates the impact of breast reduction surgery on lung function and finds that most studies indicate improved respiratory parameters in women with macromastia. However, the clinical and functional significance of these improvements is still debated.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Health Care Sciences & Services
Giuseppe Visconti, Alessandro Bianchi, Marzia Salgarello, Alba Di Leone, Akitatsu Hayashi, Riccardo Masetti, Gianluca Franceschini
Summary: This study presented the experience of lymphatic transfer in 30 patients with extremity lymphedema and 15 patients with post-traumatic lower extremity soft tissue defects. Results indicated that LFT may be a valid treatment option, reducing lymphedema index and improving stability in patients.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Surgery
Matteo Torresetti, Alessandro Scalise, Michele Pelliccioni, Francesco Mauro Junior Taddei, Giovanni Di Benedetto
Summary: This retrospective study evaluated the role of drains in sentinel lymph node biopsy (SLNB) and found that the use of drains prolongs hospital stays and the duration of postoperative antibiotic therapy, resulting in higher costs.
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN
(2022)
Review
Surgery
Alessandro Bianchi, Marzia Salgarello, Akitatsu Hayashi, Giuseppe Visconti
Summary: Upper limb lymphedema is a common, chronic, progressive, and debilitating disease that affects a growing population of cancer survivors. The current gold standard is an integrated approach, including conservative and surgical treatment, with a special focus on offering lymphatic surgery early to ameliorate symptoms and halt disease progression.
Article
Surgery
Antonio Stanizzi, Matteo Torresetti, Michele Salati, Giovanni Di Benedetto
Summary: Lung hernia following minimally invasive cardiac surgery is rare, and the repair method remains debatable. A case study showed successful repair using a non-cross linked acellular dermal matrix (ADM), indicating its safety and reliability for this condition.