Mind the gap: Models in multiple species needed for therapeutic development in Huntington's disease
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Title
Mind the gap: Models in multiple species needed for therapeutic development in Huntington's disease
Authors
Keywords
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Journal
MOVEMENT DISORDERS
Volume 29, Issue 11, Pages 1397-1403
Publisher
Wiley
Online
2014-08-23
DOI
10.1002/mds.26008
References
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Note: Only part of the references are listed.- A two years longitudinal study of a transgenic Huntington disease monkey
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- (2014) A. J. Morton et al. HUMAN MOLECULAR GENETICS
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- (2013) Elise Gieling et al. Behavioral and Brain Functions
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- Selective Roles of Normal and Mutant Huntingtin in Neural Induction and Early Neurogenesis
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- Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction
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- (2011) Ignacio Munoz-Sanjuan et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2009) A. E. Molero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Towards a transgenic model of Huntington’s disease in a non-human primate
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