Tricyclic antidepressants delay the need for dopaminergic therapy in early Parkinson's disease

A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes

(2011) Olivier Rascol et al.   LANCET NEUROLOGY

Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation

(2011) Young C. Chung et al.   NEUROPHARMACOLOGY

Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

(2011) Jürgen Zschocke et al.   NEUROPSYCHOPHARMACOLOGY

Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity

(2011) Wayne Chadwick et al.   PLoS One

Antidepressant Treatment Restores Brain-Derived Neurotrophic Factor Serum Levels and Ameliorates Motor Function in Parkinson Disease Patients

(2010) Valerio Ricci et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Paroxetine Prevents Loss of Nigrostriatal Dopaminergic Neurons by Inhibiting Brain Inflammation and Oxidative Stress in an Experimental Model of Parkinson's Disease

(2010) Y. C. Chung et al.   JOURNAL OF IMMUNOLOGY

Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial

(2010) Paolo Barone et al.   LANCET NEUROLOGY

Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus

(2009) Yinchuan Jin et al.   BRAIN RESEARCH

Amitriptyline is a TrkA and TrkB Receptor Agonist that Promotes TrkA/TrkB Heterodimerization and Has Potent Neurotrophic Activity

(2009) Sung-Wuk Jang et al.   CHEMISTRY & BIOLOGY

The impact of treatment of depression on quality of life, disability and relapse in patients with Parkinson's disease

(2009) Matthew Menza et al.   MOVEMENT DISORDERS

Comparative responsiveness of Parkinson's disease scales to change over time

(2009) Anette Schrag et al.   MOVEMENT DISORDERS

The Effects of Antidepressants in Parkinson’s Disease: A Meta-Analysis

(2008) Pasquale G. Frisina et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

UPDRS activity of daily living score as a marker of Parkinson's disease progression

(2008) Madaline B. Harrison et al.   MOVEMENT DISORDERS

MIXED LINEAGE KINASE INHIBITOR CEP- 1347 FAILS TO DELAY DISABILITY IN EARLY PARKINSON DISEASE

(2008) L. H. Wang et al.   NEUROLOGY

A controlled trial of antidepressants in patients with Parkinson disease and depression

(2008) M. Menza et al.   NEUROLOGY

Association of Changes in Norepinephrine and Serotonin Transporter Expression with the Long-Term Behavioral Effects of Antidepressant Drugs

(2008) Zaorui Zhao et al.   NEUROPSYCHOPHARMACOLOGY

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model

(2007) Qi Peng et al.   EXPERIMENTAL NEUROLOGY