Article
Medicine, General & Internal
Tian Xu, Zhao-Sheng Li, Wei Fang, Lan-Xiao Cao, Guo-Hua Zhao
Summary: This article discusses a case of a PD patient with concomitant Othello syndrome and impulse control disorders, emphasizing the importance of early identification of OS and proposing treatment methods involving reducing dopamine agonist dosage and prescribing quetiapine.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Clinical Neurology
Gustavo Campos de Franca, Henrique Carneiro de Barros Barreto, Thiago Paranhos, Julio Cesar Nunes, Ricardo de Oliveira-Souza
Summary: This case report describes a 95-year-old woman with degenerative dementia who experienced a radical change in personality and eventually developed catatonic stupor. Magnetic resonance imaging revealed asymmetric frontotemporal and parietal atrophy. The case highlights the link between frontotemporal injury and behavioral disinhibition, as well as the involvement of the parietal cortex in the development of catatonic stupor.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
Austin W. Blum, Jon E. Grant
Summary: Compulsive sexual behavior disorder (CSBD) is a common disorder with limited treatment options. This case series suggests that N-acetylcysteine (NAC) may be a promising treatment option for CSBD patients, including those who have failed traditional therapies.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Medicine, General & Internal
Takahiro Kanai, Takane Ito, Jun Aoyagi, Takanori Yamagata
Summary: This study reminds us of the existence of membranous nephropathy without vacuolated podocytes in Fabry disease during treatment.
Article
Clinical Neurology
Carlos Silva, Marta Rebelo, Ines Chendo
Summary: Neuropsychiatric symptoms and syndromes, including Dopamine Dysregulation Syndrome, are common but often overlooked non-motor symptoms of Parkinson's Disease. This article presents a case of a 55-year-old male with Parkinson's Disease who developed Dopamine Dysregulation Syndrome, mania, and compulsive buying. The article also reviews the risk factors and therapeutic management of Dopamine Dysregulation Syndrome in Parkinson's Disease.
FRONTIERS IN NEUROLOGY
(2023)
Article
Geriatrics & Gerontology
Afaf Albalawi
Summary: There is limited evidence on the optimal therapeutic approach for neuropsychiatric symptoms associated with Parkinson's disease dementia (PDD). Selective serotonin reuptake inhibitors (SSRIs) are not recommended for first-line treatment in PDD patients due to limited efficacy and potential adverse effects. This report presents a case of a PDD patient who developed deep venous thrombosis and hyponatremia after initiating citalopram treatment.
Article
Health Care Sciences & Services
Teresa Mena-Moreno, Lucero Munguia, Rosario Granero, Ignacio Lucas, Almudena Sanchez-Gomez, Ana Camara, Yaroslau Compta, Francesc Valldeoriola, Fernando Fernandez-Aranda, Anne Sauvaget, Jose M. Menchon, Susana Jimenez-Murcia
Summary: This study presents a case of a patient with impulse control disorder (ICD) triggered by dopaminergic medication for Parkinson disease (PD). A combined intervention using cognitive behavioral therapy (CBT) and a serious game (e-Estesia) was carried out to reduce the harm of the disease. The results showed positive outcomes in terms of improved emotion regulation, reduced emotional distress, and lower levels of impulsivity.
JMIR SERIOUS GAMES
(2022)
Article
Neurosciences
Thomas Kinateder, Daniela Marinho, Doreen Gruber, Laura Hatzler, Georg Ebersbach, Florin Gandor
Summary: Sexual dysfunctions are common but underreported in Parkinson's disease, with male patients being more affected. Erectile dysfunction and orgasm dysfunction are the most common complaints. SD has negative impacts on partnership and quality of life and should be routinely assessed.
Article
Medicine, General & Internal
Jie Li, Yun Liu, Lei Peng, Jian Liu, Zhi-Dong Cao, Miao He
Summary: Kyphoplasty has obvious short-term therapeutic efficacy for Kummell's disease. However, complications such as postoperative refracture and adjacent vertebral fracture can still occur in the long term. In patients with Parkinson's disease, an intervertebral bridge may be formed after these fractures, providing new stability.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Neurosciences
Bowen Chang, Jiaming Mei, Chi Xiong, Peng Chen, Manli Jiang, Chaoshi Niu
Summary: This study reported a case of a PD patient who significantly improved symptoms after undergoing bilateral globus pallidus interna combined with subthalamic nucleus variable frequency DBS treatment, exploring a new approach for treating dystonia disorders.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Immunology
Linxia Deng, Yaxian Chen, Xiufen Hu, Jianhua Zhou, Yu Zhang
Summary: Interstitial lung disease (ILD) as an initial manifestation of lupus is rare in young children. Prompt work-up for connective tissue disease (CTD) should be considered in young children with ILD. Pirfenidone might be a useful add-on therapy with immunosuppressive agents for refractory CTD-ILD in pediatric patients. Further clinical trials are needed to assess the efficiency and safety of this combination therapy for refractory CTD-ILD.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Immunology
Ruixia Li, Xiaofei Li, He Zhou, Yanting Shi, Fang Wang, Tong Wu, Jie Liang
Summary: This case report describes a 50-year-old female patient with intestinal BD who had a positive response to anti-TNF-alpha biologics but not to conventional drugs. After treatment with VDZ, the patient showed significant improvement in abdominal pain and joint pain, and complete healing of intestinal mucosal ulcers. However, oral and vulvar ulcers required the addition of thalidomide for resolution.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Immunology
Boyun Yang, Hanxiao Yu, Minyue Jia, Wo Yao, Ran Diao, Bohui Li, Yongfang Wang, Ting Li, Liuya Ge, Huiying Wang
Summary: This article reports the treatment of a patient with Kimura disease (KD). The patient underwent various treatments, and ultimately achieved significant improvement through the use of dupilumab.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Tomaz Rus, Jernej Mlakar, Jan Jamsek, Maja Trost
Summary: In this case study, FDG PET imaging was used to explore the impact of multiple proteinopathies on brain metabolism and metabolic networks in a patient with clinically diagnosed sporadic Creutzfeldt-Jakob disease (sCJD) who also showed signs of Parkinson's disease (PD). The findings revealed both CJD-related and PD-related metabolic patterns in the brain. This case provides valuable insights into the complex interplay of neurodegenerative pathologies and highlights the role of metabolic brain imaging in evaluating the presence of multiple proteinopathies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Fernando Alonso-Frech, Carla Fernandez-Garcia, Victor Gomez-Mayordomo, Mariana H. G. Monje, Celia Delgado-Suarez, Clara Villanueva-Iza, Maria Jose Catalan-Alonso
Summary: Deep brain stimulation (DBS) is an effective treatment for Parkinson's disease, but it can cause adverse effects. This case study found that stimulation of the subthalamic nucleus (STN) using directional electrodes improved motor symptoms but resulted in uncontrollable laughter. The exact electrode placement and stimulation parameters play a crucial role in symptom improvement and adverse effects.
FRONTIERS IN NEUROLOGY
(2022)
