Article
Acoustics
M. C. E. Hooijschuur, E. B. N. J. Janssen, E. G. Mulder, A. A. Kroon, J. M. J. Meijers, J. J. Brugts, B. C. T. Van Bussel, S. M. J. Van Kuijk, M. E. A. Spaanderman, C. Ghossein-Doha
Summary: This study aimed to develop a prediction model for identifying the development of hypertension within 10 years following pre-eclampsia in women who were initially normotensive. The model, based on five variables, demonstrated good-to-excellent discriminative ability, with high sensitivity and specificity for predicting hypertension.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
K. Hilden, A. Magnuson, S. Montgomery, E. Schwarcz, U. Hanson, D. Simmons, H. Backman
Summary: This study investigates the associations between pre-eclampsia, gestational diabetes mellitus (GDM), and cardiovascular disease (CVD). The results show that both pre-eclampsia and GDM are independent risk factors for later CVD. The association between pre-eclampsia and CVD is not modified by body mass index (BMI). Effective CVD preventive programs for high-risk women are urgently needed.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sara Hallum, Saima Basit, Mads Kamper-Jorgensen, Thomas S. G. Sehested, Heather A. Boyd
Summary: Pre-eclampsia increases women's risk of cardiovascular disease, especially within a decade after delivery and for women aged 30-39 years. A history of pre-eclampsia can be used to identify women at increased risk of cardiovascular disease, and targeted interventions should be initiated soon after delivery.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Endocrinology & Metabolism
Sharmaine Thirunavukarasu, Faiza Ansari, Richard Cubbon, Karen Forbes, Chiara Bucciarelli-Ducci, David E. Newby, Marc R. Dweck, Oliver J. Rider, Ladislav Valkovic, Christopher T. Rodgers, Damian J. Tyler, Amrit Chowdhary, Nicholas Jex, Sindhoora Kotha, Lara Morley, Hui Xue, Peter Swoboda, Peter Kellman, John P. Greenwood, Sven Plein, Thomas Everett, Eleanor Scott, Eylem Levelt
Summary: Women with gestational diabetes mellitus (GDM) in the third trimester of pregnancy exhibit impaired myocardial contractility and higher left ventricular mass, accompanied by reductions in myocardial energetics.
Article
Clinical Neurology
Satu Kotikoski, Arttu Kurtelius, Heidi J. Nurmonen, Juho Paavola, Virve Karkkainen, Terhi J. Huuskonen, Jukka Huttunen, Timo Koivisto, Mikael von Und zu Fraunberg, Juha E. Jaaskelainen, Antti E. Lindgren
Summary: This study found a higher prevalence of pre-eclampsia in patients with saccular intracranial aneurysms (sIAs) compared to the general population, with sIA patients with pre-eclampsia more frequently having irregularly shaped aneurysms. Further research is needed to determine if a history of pre-eclampsia indicates an elevated risk for sIA formation or rupture.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Xi-Meng Wang, Yan Gao, Johan G. Eriksson, Weiqing Chen, Yap Seng Chong, Kok Hian Tan, Cuilin Zhang, Lei Zhou, Ling-Jun Li
Summary: In this study, serum metabolites associated with GDM and postpartum AGM were identified among women in Singapore. These metabolites combined with traditional risk factors showed higher indicative value in predicting AGM compared to traditional models, shedding light on the pathophysiology of the transition from GDM to AGM.
SCIENTIFIC REPORTS
(2021)
Review
Endocrinology & Metabolism
Lana R. Flachs Madsen, Stine Gerdoe-Kristensen, Jeannet Lauenborg, Peter Damm, Ulrik S. Kesmodel, Elsebeth Lynge
Summary: This article reviews the association between gestational diabetes mellitus (GDM) and other diseases, finding evidence of associations with kidney diseases and liver disease, particularly in women with postpartum type 2 diabetes mellitus (T2DM). The association with breast cancer has been extensively studied but with conflicting results. Limited and inconsistent results were found for other cancers and no studies were found on thyroid diseases or short-term/long-term mortality in women with a history of GDM.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Endocrinology & Metabolism
Maleesa M. Pathirana, Zohra Lassi, Anna Ali, Margaret Arstall, Claire T. Roberts, Prabha H. Andraweera
Summary: This study found that women with previous Gestational Diabetes Mellitus (GDM) have significantly higher risk for conventional cardiovascular disease (CVD) risk factors compared to women without previous GDM, with some risk factors observable within less than a year post-partum. Women with GDM may benefit from early screening for modifiable CVD risk factors.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2021)
Review
Medicine, General & Internal
Fahmy Hanna, Pensee Wu, Adrian Heald, Anthony Fryer
Summary: Gestational diabetes mellitus (GDM) and polycystic ovarian syndrome (PCOS) are highly prevalent risk factors for type 2 diabetes mellitus in young women. Current screening strategies for these conditions suffer from lack of consensus, poor adherence, and a generic approach that misses opportunities for early and personalized prevention interventions. New targeted screening strategies that incorporate early, prevention-focused testing and personalized risk stratification are urgently needed.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Review
Medicine, General & Internal
Jennifer Fu, Ravi Retnakaran
Summary: Gestational diabetes mellitus is a chronic cardiometabolic disorder in pregnancy, which identifies high-risk women for early intervention and risk modification to prevent the development of diabetes and heart disease.
Article
Endocrinology & Metabolism
Jue Wang, Xiao-Hui Gong, Ting Peng, Jiang-Nan Wu
Summary: Maternal thyroid dysfunction during pregnancy is associated with the risk of gestational hypertension and diabetes, with variations based on gestational age at diagnosis and thyroid autoantibody status.
ENDOCRINE PRACTICE
(2021)
Article
Cardiac & Cardiovascular Systems
Anum Aslam, Sheneli Perera, Monique Watts, David Kaye, Jaime Layland, Stephen J. Nicholls, James Cameron, Sarah Zaman
Summary: More than a quarter of women treated with PCI for CAD had experienced a past pregnancy-related vascular complication, yet medical providers were not obtaining a history of these 'non-traditional' cardiovascular risk factors.
HEART LUNG AND CIRCULATION
(2021)
Review
Cardiac & Cardiovascular Systems
Raeesa Bhorat, Ismail Bhorat, Olive P. Khaliq, Jagidesa Moodley
Summary: This study aimed to investigate the impact of pre-eclampsia and HIV infection on cardiac function. Cardiovascular diseases have been found to affect pregnancies complicated by both HIV and pre-eclampsia, with pre-eclampsia being associated with both systolic and diastolic dysfunction. There may be a bidirectional pathophysiology, where placenta-mediated factors can influence cardiac function, or pre-existing cardiovascular disease can predispose to pre-eclampsia. Further research is needed to understand the link between these diseases for the development of novel therapeutic interventions.
CARDIOVASCULAR JOURNAL OF AFRICA
(2023)
Article
Endocrinology & Metabolism
Maleesa M. Pathirana, Prabha H. Andraweera, Emily Aldridge, Shalem Y. Leemaqz, Madeline Harrison, Jade Harrison, Petra E. Verburg, Margaret A. Arstall, Gustaaf A. Dekker, Claire T. Roberts
Summary: Gestational diabetes mellitus may lead to abnormal cardio-metabolic risk factors in women and their children three years after childbirth, but early pregnancy BMI and socioeconomic index may act as mediators.
ACTA DIABETOLOGICA
(2022)
Article
Obstetrics & Gynecology
Ravi Retnakaran, Baiju R. Shah
Summary: This study aimed to assess the changes in cardiovascular risk factors before pregnancy in women who develop pre-eclampsia and those who do not. The results showed that women who developed pre-eclampsia had abnormal values in multiple indicators before pregnancy, and these abnormalities worsened over the years before pregnancy.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
C. Noel Bairey Merz, Eduardo Marban
CIRCULATION RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Harmony R. Reynolds, C. Noel Bairey Merz, Colin Berry, Rohit Samuel, Jacqueline Saw, Nathaniel R. Smilowitz, Ana Carolina do A. H. de Souza, Robert Sykes, Viviany R. Taqueti, Janet Wei
Summary: Ischemic heart disease is the leading cause of mortality in women and requires gender-specific risk stratification for prevention, diagnosis, and treatment. Recent research has improved understanding of cardiovascular disease in women, including mechanisms of ischemia with no obstructive coronary arteries and myocardial infarction with no obstructive coronary arteries. Despite progress, sex differences in ischemic heart disease outcomes persist.
CIRCULATION RESEARCH
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Natalie A. Bello, C. Noel Bairey Merz, Susan Cheng
CIRCULATION RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Timothy D. Henry, C. Noel Bairey Merz, Janet Wei, Michel T. Corban, Odayme Quesada, Sandy Joung, Christine L. Kotynski, Jian Wang, Michelle Lewis, Ann M. Schumacher, Ronnda L. Bartel, Hiroshi Takagi, Vishal Shah, Anna Lee, William K. Sietsema, Douglas W. Losordo, Amir Lerman
Summary: This study evaluated the safety and efficacy of intracoronary CD34+ cell therapy in patients with coronary microvascular dysfunction. The results showed that patients receiving CD34+ cell therapy had improved coronary flow reserve, reduced angina symptoms, and improved quality of life after 6 months of treatment. This study supports the potential therapeutic role of CD34+ cells in patients with microvascular angina.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Joseph E. Ebinger, Yunxian Liu, Matthew Driver, Hongwei Ji, C. Noel Bairey Merz, Florian Rader, Christine M. Albert, Susan Cheng
Summary: Despite improvements in overall hypertension control, hospitalization rates for hypertensive crises, especially among men, have steadily increased, along with an increase in the burden of cardiovascular conditions.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Letter
Cardiac & Cardiovascular Systems
Adele Pope, Louise Thomson, Stephanie Cantu, Gayatri Setia, Nare Torosyan, Noel Bairey Merz, Katelyn Atk Ins, Eric M. Anderson, Susan Cheng, Balaji Tamar Appoo
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2022)
Letter
Cardiac & Cardiovascular Systems
Alan C. Kwan, Jesse Navarrette, Patrick Botting, Melanie T. Chen, Janet Wei, C. Noel Bairey Merz, Joseph E. Ebinger, Susan Cheng
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Christine Pacheco, Judy Luu, Puja K. Mehta, Janet Wei, Martha Gulati, C. Noel Bairey Merz
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Susan L. Ivey, Hattie Rees Hanley, Catrina Taylor, Eveline Stock, Nirali Vora, Jenny Woo, Sara Johnson, C. Noel Bairey Merz
Summary: Cardiovascular diseases are the leading causes of death among women of all ages. Efforts to reduce CVD in women have stagnated over the past decade, with an increase observed among younger women and women of color. Policy levers are recommended to address CVD in women, including promoting screening for risk factors, enhancing education, and providing support resources.
CLINICAL CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Judy M. Luu, Janet Wei, Chrisandra L. Shufelt, Anum Asif, Benita Tjoe, Paul Theriot, C. Noel Bairey Merz
Summary: This survey reveals heterogeneity in the management of ischemia with no obstructive coronary artery disease among US cardiologists, supporting the need for guideline development and highlighting knowledge gaps in therapeutic management and research education for this condition.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Carl J. Pepine, C. Noel Bairey Merz
EUROPEAN HEART JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Mario Gaudino, Stephen E. Fremes, Roxana Mehran, C. Noel Bairey Merz
Review
Peripheral Vascular Disease
Paul Marano, Janet Wei, C. Noel Bairey Merz
Summary: This article reviews recent research progress related to coronary microvascular dysfunction (CMD) and its association with multiple cardiovascular disease processes. CMD is prevalent in patients with signs and symptoms of ischemia and no obstructive epicardial coronary artery disease (INOCA), particularly in women. CMD is associated with adverse outcomes, including the development of heart failure with preserved ejection fraction, in various patient populations. Stratified medical therapy based on invasive coronary function testing can improve symptoms in patients with INOCA.
CURRENT ATHEROSCLEROSIS REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Sadiya S. Khan, Lucia C. Petito, Xiaoning Huang, Katharine Harrington, Rebecca B. McNeil, Natalie A. Bello, C. Noel Bairey Merz, Eliza C. Miller, Rupa Ravi, Christina Scifres, Janet M. Catov, Victoria L. Pemberton, Jasmina Varagic, Phyllis C. Zee, Lynn M. Yee, Mitali Ray, Jin Kyung Kim, Abbi D. Lane-Cordova, Jennifer Lewey, Lauren H. Theilen, George R. Saade, Philip Greenland, William A. Grobman
Summary: This study found a significant association between early pregnancy obesity and postpartum hypertension, hyperlipidemia, and diabetes risk. Adverse pregnancy outcomes were related to increased incidence of postpartum hypertension and hyperlipidemia. However, these adverse pregnancy outcomes only partially mediated the association between early pregnancy obesity and postpartum hypertension.
CIRCULATION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Maggie Wang, Nare Torosyan, C. Noel Bairey-Merz, Janet Wei, Chrisandra L. Shufelt
Summary: Resident education on cardiac rehabilitation (CR) significantly improved internal medicine residents' knowledge and attitudes towards CR, which also led to a modest increase in referral rates.
AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)