Immunologic Aspects of Multiple Sclerosis

Interferon-beta Inhibits Th17 Cell Differentiation in Patients with Multiple Sclerosis

(2012) Vinod S. Ramgolam et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Immunomodulatory Effects of IFN-β and Lovastatin on Immunophenotype of Monocyte-Derived Dendritic Cells in Multiple Sclerosis

(2010) Halina Bartosik-Psujek et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

The role of antigen presenting cells in multiple sclerosis

(2010) Emily M.L. Chastain et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Immunological mechanisms that associate with oligoclonal IgM band synthesis in multiple sclerosis

(2010) Luisa M. Villar et al.   CLINICAL IMMUNOLOGY

Overlapping and distinct mechanisms of action of multiple sclerosis therapies

(2010) J.J. Graber et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Interferon beta inhibits the Th17 cell-mediated autoimmune response in patients with relapsing–remitting multiple sclerosis

(2010) Xin Zhang et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Th17/Th1 phenotype in demyelinating disease

(2010) L.J. Edwards et al.   CYTOKINE

Confirmation of association between multiple sclerosis and CYP27B1

(2010) Emilie Sundqvist et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

CD8+Foxp3+ T cells in peripheral blood of relapsing-remitting multiple sclerosis patients

(2010) Giovanni Frisullo et al.   HUMAN IMMUNOLOGY

Identification of an immediate Foxp3−precursor to Foxp3+regulatory T cells in peripheral lymphoid organs of nonmanipulated mice

(2010) Sonja Schallenberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of dendritic cells in CNS autoimmunity

(2010) Alla L. Zozulya et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Increased expression of B cell-associated regulatory cytokines by glatiramer acetate in mice with experimental autoimmune encephalomyelitis

(2010) Sakhina Begum-Haque et al.   JOURNAL OF NEUROIMMUNOLOGY

Epstein-Barr Virus Latent Infection and BAFF Expression in B Cells in the Multiple Sclerosis Brain: Implications for Viral Persistence and Intrathecal B-Cell Activation

(2010) Barbara Serafini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Immunomodulatory effects of vitamin D on monocyte-derived dendritic cells in multiple sclerosis

(2010) Halina Bartosik-Psujek et al.   Multiple Sclerosis Journal

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

Multiple sclerosis genetics—is the glass half full, or half empty?

(2010) Jorge R. Oksenberg et al.   Nature Reviews Neurology

Disturbed regulatory T cell homeostasis in multiple sclerosis

(2010) Koen Venken et al.   TRENDS IN MOLECULAR MEDICINE

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

Immunomodulatory effects of Vitamin D in multiple sclerosis

(2009) J. Correale et al.   BRAIN

Multiple sclerosis and the major histocompatibility complex

(2009) Sreeram V Ramagopalan et al.   CURRENT OPINION IN NEUROLOGY

EAE: An immunologist's magic eye

(2009) Gurumoorthy Krishnamoorthy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Th9 and allergic disease

(2009) Pejman Soroosh et al.   IMMUNOLOGY

Regulatory and pro-inflammatory phenotypes of myelin basic protein-autoreactive T cells in multiple sclerosis

(2009) J. Hong et al.   INTERNATIONAL IMMUNOLOGY

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epstein-Barr virus (EBV)–encoded small RNA is released from EBV-infected cells and activates signaling from toll-like receptor 3

(2009) Dai Iwakiri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

(2009) A. Jager et al.   JOURNAL OF IMMUNOLOGY

Helminth Antigens Modulate Immune Responses in Cells from Multiple Sclerosis Patients through TLR2-Dependent Mechanisms

(2009) J. Correale et al.   JOURNAL OF IMMUNOLOGY

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

Antibodies to specific EBNA-1 domains and HLA DRB1⁎1501 interact as risk factors for multiple sclerosis☆

(2009) Peter Sundström et al.   JOURNAL OF NEUROIMMUNOLOGY

Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis

(2009) Daniela Pohl et al.   JOURNAL OF NEUROLOGY

Epstein-Barr virus is associated with grey matter atrophy in multiple sclerosis

(2009) R Zivadinov et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

In the beginning

(2009) Richard M. Ransohoff   NATURE

Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS

(2009) F. Sellebjerg et al.   NEUROLOGY

Interferon-  mechanisms of action in multiple sclerosis

(2009) S. Dhib-Jalbut et al.   NEUROLOGY

Glucocorticoids increase CD4+CD25highcell percentage and Foxp3 expression in patients with multiple sclerosis

(2008) M. Braitch et al.   ACTA NEUROLOGICA SCANDINAVICA

Homogeneity of active demyelinating lesions in established multiple sclerosis

(2008) Esther C. W. Breij et al.   ANNALS OF NEUROLOGY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

Regulatory T cells fail to suppress CD4+ T-bet+T cells in relapsing multiple sclerosis patients

(2008) Giovanni Frisullo et al.   IMMUNOLOGY

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

(2008) Beichu Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE

(2008) Marloes van Zwam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Combination treatment of Glatiramer Acetate and Minocycline affects phenotype expression of blood monocyte-derived dendritic cells in Multiple Sclerosis patients

(2008) Maddalena Ruggieri et al.   JOURNAL OF NEUROIMMUNOLOGY

A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis

(2008) Howard L. Weiner   JOURNAL OF NEUROLOGY

Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

(2008) Benjamin M Segal et al.   LANCET NEUROLOGY

B cells and multiple sclerosis

(2008) Diego Franciotta et al.   LANCET NEUROLOGY

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Novel therapeutic strategies for multiple sclerosis — a multifaceted adversary

(2008) Rocio S. Lopez-Diego et al.   NATURE REVIEWS DRUG DISCOVERY

Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis

(2008) P. L. De Jager et al.   NEUROLOGY

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

(2008) T. Korn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-17—Extended Features of a Key Player in Multiple Sclerosis

(2007) Ralf Gold et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY