Characteristics and critical function of CD8+ T cells in the Toxoplasma-infected brain

Heterogeneous CD8+ T Cell Migration in the Lymph Node in the Absence of Inflammation Revealed by Quantitative Migration Analysis

(2015) Edward J. Banigan et al.   PLoS Computational Biology

PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE

(2014) Karthik Sathiyanadan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

VCAM-1/α4β1 Integrin Interaction Is Crucial for Prompt Recruitment of Immune T Cells into the Brain during the Early Stage of Reactivation of Chronic Infection with Toxoplasma gondii To Prevent Toxoplasmic Encephalitis

(2014) Qila Sa et al.   INFECTION AND IMMUNITY

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells

(2014) Tilman Schneider-Hohendorf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In Vivo Polarization of IFN-  at Kupfer and Non-Kupfer Immunological Synapses during the Clearance of Virally Infected Brain Cells

(2014) C. Barcia et al.   JOURNAL OF IMMUNOLOGY

Astrocyte gp130 Expression Is Critical for the Control of Toxoplasma Encephalitis

(2014) K. Drogemuller et al.   JOURNAL OF IMMUNOLOGY

CXCR3 Mediates Region-Specific Antiviral T Cell Trafficking within the Central Nervous System during West Nile Virus Encephalitis

(2014) B. Zhang et al.   JOURNAL OF IMMUNOLOGY

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

(2014) Christopher D. Dupont et al.   PLoS Pathogens

Fatal cerebral malaria: a venous efflux problem

(2014) Ute Frevert et al.   Frontiers in Cellular and Infection Microbiology

Donor CD8+T Cells Prevent Toxoplasma gondii De-Encystation but Fail To Rescue the Exhausted Endogenous CD8+T Cell Population

(2013) Rajarshi Bhadra et al.   INFECTION AND IMMUNITY

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

(2013) Bernd H. Zinselmeyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Kinetics of Myelin Antigen Uptake by Myeloid Cells in the Central Nervous System during Experimental Autoimmune Encephalomyelitis

(2013) R. A. Sosa et al.   JOURNAL OF IMMUNOLOGY

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

(2013) Dmitri Lodygin et al.   NATURE MEDICINE

Axons are injured by antigen-specific CD8+ T cells through a MHC class I- and granzyme B-dependent mechanism

(2013) Brian M. Sauer et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14+CD16+ Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

(2013) Dionna W. Williams et al.   PLoS One

Chitinase Dependent Control of Protozoan Cyst Burden in the Brain

(2012) J. Philip Nance et al.   PLoS Pathogens

Redefining Chronic Toxoplasmosis—A T Cell Exhaustion Perspective

(2012) Rajarshi Bhadra et al.   PLoS Pathogens

Interferon-gamma- and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brain

(2011) Yasuhiro Suzuki et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

(2011) Silvia S. Kang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Behavior and Trafficking of Dendritic Cells within the Brain during Toxoplasmic Encephalitis

(2011) Beena John et al.   PLoS Pathogens

Removal of Toxoplasma gondii Cysts from the Brain by Perforin-Mediated Activity of CD8+ T Cells

(2010) Yasuhiro Suzuki et al.   AMERICAN JOURNAL OF PATHOLOGY

CNS-derived CCL21 is both sufficient to drive homeostatic CD4+ T cell proliferation and necessary for efficient CD4+ T cell migration into the CNS parenchyma following Toxoplasma gondii infection

(2010) Corinne C. Ploix et al.   BRAIN BEHAVIOR AND IMMUNITY

Toxoplasma gondii: The severity of toxoplasmic encephalitis in C57BL/6 mice is associated with increased ALCAM and VCAM-1 expression in the central nervous system and higher blood–brain barrier permeability

(2010) Neide Maria Silva et al.   EXPERIMENTAL PARASITOLOGY

CCR7-Dependent Immunity during Acute Toxoplasma gondii Infection

(2010) S. Noor et al.   INFECTION AND IMMUNITY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphoid chemokines in the CNS

(2010) Stephen J. Lalor et al.   JOURNAL OF NEUROIMMUNOLOGY

Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions

(2010) Anita A Koshy et al.   NATURE METHODS

Absence of Both IL-7 and IL-15 Severely Impairs the Development of CD8+ T Cell Response against Toxoplasma gondii

(2010) Rajarshi Bhadra et al.   PLoS One

Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

(2010) L. M. Wakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis

(2009) Georgios Pappas et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Persistent Viral Infection Elevates Central Nervous System MHC Class I through Chronic Production of Interferons

(2009) P. Truong et al.   JOURNAL OF IMMUNOLOGY

Dynamic Imaging of T Cell-Parasite Interactions in the Brains of Mice Chronically Infected with Toxoplasma gondii

(2009) Marie Schaeffer et al.   JOURNAL OF IMMUNOLOGY

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamics of Neutrophil Migration in Lymph Nodes during Infection

(2008) Tatyana Chtanova et al.   IMMUNITY

Parasite Stage–Specific Recognition of EndogenousToxoplasma gondii–Derived CD8+T Cell Epitopes

(2008) Eva‐Maria Frickel et al.   JOURNAL OF INFECTIOUS DISEASES

Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection

(2008) Gretchen Hermes et al.   Journal of Neuroinflammation

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

T Cells' Immunological Synapses Induce Polarization of Brain Astrocytes In Vivo and In Vitro: A Novel Astrocyte Response Mechanism to Cellular Injury

(2008) Carlos Barcia et al.   PLoS One