Transition metal-free addition of dithiocarbamates to alkynes: one-pot regioselective synthesis of S-vinyl dithiocarbamates under solvent-free conditions

A convenient, green, and efficient procedure for the synthesis of S-vinyl dithiocarbamates by a simple one-pot three-component condensation of an amine, carbon disulfide, and alkynes is described in the absence of any transition metal catalyst and under solvent-free conditions. This clean and improved method selectively furnishes the corresponding (Z)-S-vinyl dithiocarbamates in good to excellent yields. The reaction is clean with simple product workup and is carried out at 80 A degrees C.