4.2 Article

One-pot, three-component synthesis of 2,3-dihydroquinazolin-4(1H)-ones using p-toluenesulfonic acid-paraformaldehyde copolymer as an efficient and reusable catalyst

Journal

MONATSHEFTE FUR CHEMIE
Volume 141, Issue 10, Pages 1113-1115

Publisher

SPRINGER WIEN
DOI: 10.1007/s00706-010-0376-3

Keywords

2,3-Dihydroquinazolin-4(1H)-ones; Heterogeneous catalyst; Copolymer-PTSA

Funding

  1. Research Council of Islamic Azad University, Najafabad Branch

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p-Toluenesulfonic acid-paraformaldehyde copolymer (copolymer-PTSA) catalyzes the three-component, one-pot condensation reaction of isatoic anhydride, ammonium salts or aromatic and aliphatic amines, and aldehydes in refluxing ethanol. The catalyst is reusable and could be recycled for several runs without any decrease in its efficiency.

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