Journal
MONATSHEFTE FUR CHEMIE
Volume 139, Issue 4, Pages 447-457Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-008-0895-3
Keywords
RNA folding kinetics; Co-transcriptional folding; folding pathway; metastable structures
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The term RNA folding is often used synonymously with the prediction of equilibrium structures. Yet many RNAs function thanks to their ability to undergo structural changes. In this contribution we present a systematic overview of existing approaches to the prediction of RNA folding kinetics, and in particular discuss the strengths and limitations of each method.
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