Synthesis, Biological Evaluation and Structure-Activity Relationships of New Quinoxaline Derivatives as Anti-Plasmodium falciparum Agents

Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides

(2013) Frans J. Smit et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient Synthesis of Quinoxaline Derivatives by Selective Modification of 3-Chloro-6-fluoroquinoxalin-2(1H)-one 4-Oxide

(2013) Jan Maichrowski et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Simple Synthesis of Quinoxalin-2(1H)-oneN-Oxides fromN-Aryl-2-nitrosoanilines and Alkylated Cyanoacetic Esters

(2013) Magdalena Królikiewicz et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

New Amide Derivatives of Quinoxaline 1,4-di-N-Oxide with Leishmanicidal and Antiplasmodial Activities

(2013) Carlos Barea et al.   MOLECULES

Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores

(2012) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

(2012) Carlos Barea et al.   MOLECULES

New 1,4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterium tuberculosis agents

(2011) Enrique Torres et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities

(2011) Carlos Barea et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Biological Evaluation of New Quinoxaline Derivatives as Antioxidant and Anti-Inflammatory Agents

(2011) Asunción Burguete et al.   Chemical Biology & Drug Design

Trypanocidal properties, structure–activity relationship and computational studies of quinoxaline 1,4-di-N-oxide derivatives

(2011) Yannick Estevez et al.   EXPERIMENTAL PARASITOLOGY

3-TrifluoromethylquinoxalineN,N′-Dioxides as Anti-Trypanosomatid Agents. Identification of Optimal Anti-T. cruziAgents and Mechanism of Action Studies

(2011) Diego Benitez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and bio-evaluation of alkylaminoaryl phenyl cyclopropyl methanones as antitubercular and antimalarial agents

(2010) Arya Ajay et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti-Mycobacterium tuberculosis agents

(2010) Saioa Ancizu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds

(2010) Eric M. Guantai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives

(2010) Elsa Moreno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance

(2009) Umashankar Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

(2009) Renate H. Hans et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new chalcone derivatives containing acridinyl moiety with potential antimalarial activity

(2009) V. Tomar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-leishmanial and structure-activity relationship of ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives

(2009) Asunción Burguete et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of Quinoxaline-2-Carboxylate 1,4-Di-N-Oxide Derivatives in Experimental Tuberculosis

(2008) E. Vicente et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selective activity against Mycobacterium tuberculosis of new quinoxaline 1,4-di-N-oxides

(2008) Esther Vicente et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and structure–activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents

(2008) Esther Vicente et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antiplasmodial Activity of 3-Furyl and 3-Thienylquinoxaline-2-carbonitrile 1,4-Di-N-oxide Derivatives

(2008) Esther Vicente et al.   MOLECULES

Antiplasmodial structure–activity relationship of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide derivatives

(2007) Adoración Marin et al.   EXPERIMENTAL PARASITOLOGY