Emodin Protects against Diabetic Cardiomyopathy by Regulating the AKT/GSK-3β Signaling Pathway in the Rat Model
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Title
Emodin Protects against Diabetic Cardiomyopathy by Regulating the AKT/GSK-3β Signaling Pathway in the Rat Model
Authors
Keywords
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Journal
MOLECULES
Volume 19, Issue 9, Pages 14782-14793
Publisher
MDPI AG
Online
2014-09-17
DOI
10.3390/molecules190914782
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Note: Only part of the references are listed.- Emodin inhibits LPS-induced inflammatory response by activating PPAR-γ in mouse mammary epithelial cells
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- (2013) Deepti Shrimali et al. CANCER LETTERS
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- (2013) Sara Nunes et al. Cardiovascular Diabetology
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- (2013) Wonhwa Lee et al. INFLAMMATION
- Characterization of Apoptosis Induced by Emodin and Related Regulatory Mechanisms in Human Neuroblastoma Cells
- (2013) Fu-Jen Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Global burden of disease—where does diabetes mellitus fit in?
- (2013) K. George M. M. Alberti et al. Nature Reviews Endocrinology
- Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function
- (2012) Yingmei Zhang et al. BMC Medicine
- Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms
- (2012) Manuela Aragno et al. Cardiovascular Diabetology
- Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data
- (2012) Sabine Fredersdorf et al. Cardiovascular Diabetology
- Emodin Prevents Intrahepatic Fat Accumulation, Inflammation and Redox Status Imbalance During Diet-Induced Hepatosteatosis in Rats
- (2012) Anna Alisi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis
- (2012) Sheng-Zhang Lin et al. PLoS One
- The Critical Role of Astragalus Polysaccharides for the Improvement of PPRAα-Mediated Lipotoxicity in Diabetic Cardiomyopathy
- (2012) Wei Chen et al. PLoS One
- Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes
- (2011) Hong Zhou et al. ACTA PHARMACOLOGICA SINICA
- Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy
- (2011) Dongdong Sun et al. Cardiovascular Diabetology
- Heart Disease and Stroke Statistics—2012 Update
- (2011) et al. CIRCULATION
- Overexpression of Human C-Reactive Protein Exacerbates Left Ventricular Remodeling in Diabetic Cardiomyopathy
- (2011) Yoshinori Mano et al. CIRCULATION JOURNAL
- Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment
- (2011) Inês Falcão-Pires et al. HEART FAILURE REVIEWS
- Emodin, a natural product, selectively inhibits 11β-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice
- (2010) Ying Feng et al. BRITISH JOURNAL OF PHARMACOLOGY
- Vitamin B1 Analog Benfotiamine Prevents Diabetes-Induced Diastolic Dysfunction and Heart Failure Through Akt/Pim-1–Mediated Survival Pathway
- (2010) Rajesh G. Katare et al. Circulation-Heart Failure
- Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy
- (2010) Yu-Chun Lin et al. Journal of Translational Medicine
- Diabetic cardiomyopathy, causes and effects
- (2010) Sihem Boudina et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Dominant-negative p38α mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus
- (2009) Rajarajan A. Thandavarayan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Phosphodiesterase-5 Inhibitor, Tadalafil, Protects Against Myocardial Ischemia/Reperfusion Through Protein-Kinase G-Dependent Generation of Hydrogen Sulfide
- (2009) F. N. Salloum et al. CIRCULATION
- Inactivation of GSK-3 by Metallothionein Prevents Diabetes-Related Changes in Cardiac Energy Metabolism, Inflammation, Nitrosative Damage, and Remodeling
- (2009) Y. Wang et al. DIABETES
- Hyperglycemic Crises in Adult Patients With Diabetes
- (2009) A. E. Kitabchi et al. DIABETES CARE
- Rodent models of diabetic cardiomyopathy
- (2009) H. Bugger et al. Disease Models & Mechanisms
- Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo
- (2009) Wang Chun-Guang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Anti-diabetic effects of emodin involved in the activation of PPARγ on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice
- (2009) Jianfeng Xue et al. FITOTERAPIA
- Insulin-Resistant Cardiomyopathy
- (2008) Ronald M. Witteles et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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