Journal
MOLECULES
Volume 18, Issue 3, Pages 2763-2768Publisher
MDPI AG
DOI: 10.3390/molecules18032763
Keywords
Streptomyces djakartensis NW35; (E)-2-methoxy-1,4 naphthoquinone-1-oxime; antibacterial activity
Funding
- National Key S&T Research Foundation of China [2010CB126105]
- National Natural Science Foundation of China [30871663]
- Funds of Central Colleges Basic Scientific Research Operating Expenses [QN2011117]
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The new compound Z-4-2 was isolated from the fermentation broth of Streptomyces djakartensis NW35, together with the known compound N-acetyltryptamine (Z-9-2) by bioassay-guided fractionation. Its chemical structure was elucidated as (E)-2-methoxy-1,4 naphthoquinone-1-oxime (Z-4-2) mainly by NMR analyses and MS spectral data. Their antibacterial activities against bacteria were evaluated by the filter paper method. The results of indicated that these compounds possess significant antibacterial activities.
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