Synthesis and Characterization of Celecoxib Derivatives as Possible Anti-Inflammatory, Analgesic, Antioxidant, Anticancer and Anti-HCV Agents

Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase

(2011) Kevin X. Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

(2010) Frank Narjes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pyrazolo[1,5-a]pyrimidine-based inhibitors of HCV polymerase

(2009) Janeta Popovici-Muller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New pyrazoles incorporating pyrazolylpyrazole moiety: Synthesis, anti-HCV and antitumor activity

(2009) Sayed M. Riyadh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Slow Binding Inhibition and Mechanism of Resistance of Non-nucleoside Polymerase Inhibitors of Hepatitis C Virus

(2009) Julie Qi Hang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

(2009) Hui Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

(2008) N. Kaushik-Basu et al.   NUCLEIC ACIDS RESEARCH

Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents

(2007) Adnan A. Bekhit et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY