Article
Food Science & Technology
Marta C. C. Coelho, Soudabeh Ghalamara, Debora Campos, Tania Braganca Ribeiro, Ricardo Pereira, Antonio S. Rodrigues, Jose A. Teixeira, Manuela Pintado
Summary: Tomato by-products from processing industries in Portugal have the potential to be reused as a source of bioactive compounds. However, there is a lack of reliable national data on these by-products and their physicochemical properties, which hinders effective waste management planning. In this study, selected Portugal companies were recruited to obtain representative samples of by-products, and their physicochemical composition was evaluated. Additionally, an environmentally friendly method called ohmic heating (OH) was used to explore new safe value-added ingredients from these by-products.
Article
Food Science & Technology
Bianca Souza da Costa, Marta Olivan Garcia, German Soldevilla Muro, Maria-Jose Motilva
Summary: This study focused on dehydrating industrial tomato pomace using innovative techniques (microwave and spiral flash dryer) and conventional techniques (freeze-drying and hot air-drying) to produce ingredients rich in bioactive compounds. The effect of different drying methods on the bioactive composition of the tomato by-products was analyzed. Microwave dehydration improved the retention of flavanone-like compounds and lycopene, while spiral flash drying resulted in higher concentrations of flavonols and phenolic acids. These findings suggest that drying processes using microwave and spiral flash could be promising for producing high added-value ingredients from tomato by-products.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Haijing Wang, Zhenzhen Zhang, Jia Song, Maosen Tian, Ren Li, Xia Cui
Summary: Phenolic compounds in tomato fruits were isolated and identified using ultrahigh performance liquid chromatography-quadrupole time-of-flight mass spectrometry. A total of 32 phenolic compounds were found, with 13 of them being previously unknown in tomato fruits. Nine out of the 13 previously unknown components were elucidated. The content difference of the 3 main and 10 previously unknown phenolic compounds led to significantly higher phenolic levels in wild tomato fruits compared to cultivated tomato.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Davide Lanzoni, Eva Skrivanova, Raffaella Rebucci, Antonio Crotti, Antonella Baldi, Luca Marchetti, Carlotta Giromini
Summary: The growth of the world population has led to the investigation of alternative food/feed sources, with hemp-based products being considered excellent candidates due to their nutritional and functional properties. Scientific research has focused on assessing the nutritional and functional profiles of hemp-based products, such as hempseeds, flowers, and HS protein extract. The results indicate that these products have high nutritional value and exhibit significant antioxidant activity, making them suitable for use in food/feed formulations.
Article
Chemistry, Applied
Alicia P. Cardenas-Castro, Victor M. Zamora-Gasga, Emilio Alvarez-Parrilla, Victor M. Ruiz-Valdiviezo, Koen Venema, Sonia G. Sayago-Ayerdi
Summary: This study aimed to evaluate the bioaccessible phenolic compounds in tomato and husk tomato during upper gastrointestinal digestion, as well as the production of short-chain fatty acids from indigestible fractions through in vitro fermentation. It was found that vanillic acid was the most bioaccessible phenolic compound, and 3-hydroxyphenylacetic acid was the most abundant microbial metabolite after 48 hours in both samples. Additionally, microbial metabolism of carotenoids may contribute to the presence of terpenes and their derivatives in tomato and husk tomato.
Article
Plant Sciences
Monica Yorlady Alzate Zuluaga, Karina Maria Lima Milani, Maria Begona Miras-Moren, Luigi Lucini, Fabio Valentinuzzi, Tanja Mimmo, Youry Pii, Stefano Cesco, Elisete Pains Rodrigues, Andre Luiz Martinez de Oliveira
Summary: The study investigates the individual effects of two salt-tolerant plant growth-promoting bacteria on salt-stressed tomato plants, showing that one strain was more efficient in alleviating the saline stress. Salinity significantly influenced microbial metabolism in the tomato rhizosphere, with various compounds related to salinity stress or PGPB inoculation being identified through metabolomics analysis.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Review
Biochemistry & Molecular Biology
Katalin Szabo, Laura Mitrea, Lavinia Florina Calinoiu, Bernadette-Emoke Teleky, Gheorghe Adrian Martau, Diana Plamada, Mihaela Stefana Pascuta, Silvia-Amalia Nemes, Rodica-Anita Varvara, Dan Cristian Vodnar
Summary: Polyphenols of plant origin have been found to have multiple health benefits and potential roles in preventing and treating various diseases. Apple, cereal, and tomato by-products contain different types of polyphenols, which have significant health implications for diabetes, cancer, and cardiovascular diseases. Reintegrating by-products into functional food products and personalized nutrition explores a novel direction within the circular economy concept.
Review
Nutrition & Dietetics
Beata Olas
Summary: The caper, derived from the Latin word capra meaning goat, refers to the salt-fermented floral buds of the perennial shrubs from the Capparis genus. C. spinosa is one of the most popular species, and its aromatic floral buds are collected before blooming, dried, and pickled. Capers are commonly marinated and enjoyed in vinegar, brine, or oil. They have potential as dietary supplements due to their low calorie content and abundance of bioactive phytochemicals. Research has shown that C. spinosa possesses various nutritional and biological properties, including antioxidant activity from its phenolic compounds. This paper reviews the biological properties, including toxicity, of the fruits, buds, seeds, roots, and leaves of C. spinosa.
Article
Food Science & Technology
Xiomara Patricia Perea-Dominguez, Jose Alberto Mendoza-Espinoza, Jesus Martin Solano Gonzalez, Jose Belisario Leyva-Morales, Laura Gabriela Espinosa-Alonso, Maribel Valdez-Morales
Summary: The study evaluated the antioxidant and anti-proliferative activity of phenolic compounds from tomato and tomato by-product. It was found that they are a good source of natural compounds with important antioxidant and anti-proliferative activity.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2022)
Review
Biochemistry & Molecular Biology
Ignacio Moratilla-Rivera, Marta Sanchez, Jose Antonio Valdes-Gonzalez, Maria Pilar Gomez-Serranillos
Summary: Neurodegenerative diseases (NDs) are common diseases affecting the West due to increased life expectancy. Cells accumulate oxidative damage, triggering neurodegeneration. The transcription factor Nrf2 regulates endogenous antioxidant systems and induces the transcription of genes containing ARE in response to prooxidant conditions. Natural products such as quercetin, curcumin, and terpenoids can positively modulate Nrf2, reducing oxidative damage to the nervous system. This review aims to update knowledge on the potential treatments for NDs by activating the Nrf2 pathway with secondary metabolites of health interest.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agronomy
Alberto Martinez-Alonso, Paula Garcia-Ibanez, Gloria Barzana, Micaela Carvajal
Summary: The exogenous application of flavonoids can stimulate photosynthesis and promote plant growth. It can also increase stomatal opening, leading to enhanced water and nutrient uptake. The mechanism of action of flavonoids may be associated with phenolic metabolism and the expression of aquaporins.
Article
Food Science & Technology
Marta Coelho, Carla Oliveira, Ezequiel R. Coscueta, Joao Fernandes, Ricardo N. Pereira, Jose A. Teixeira, Antonio Sebastiao Rodrigues, Manuela E. Pintado
Summary: A nutrient-rich diet is important for improving chemical signals in the gut and preventing diseases. This study found that using OH technology for extraction can increase the recovery of bioactive compounds from tomato bagasse and have positive effects on health, such as antioxidant, anti-hypertensive, prebiotic, and anti-inflammatory properties. Additionally, this study demonstrated for the first time that tomato bagasse has anti-inflammatory effects.
Review
Biochemistry & Molecular Biology
Tomislav Jurendic, Mario Scetar
Summary: Studies have found that polyphenolic compounds in chokeberries have various beneficial effects on human health, including antioxidant, anti-inflammatory, hypotensive, antiviral, anticancer, antiplatelet, antidiabetic and antiatherosclerotic activities, demonstrating significant nutritional contribution and physiological effects.
Review
Nutrition & Dietetics
Montana Camara, Virginia Fernandez-Ruiz, Maria-Cortes Sanchez-Mata, Rosa M. Camara, Laura Dominguez, Howard D. Sesso
Summary: This study aims to analyze the potential beneficial effects of tomato products on cardiovascular disease prevention and antiplatelet aggregation, as well as evaluating their health claims. The findings suggest that tomato products can help maintain normal platelet aggregation and contribute to healthy blood flow.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Cristina M. Gonzalez, Isabel Hernando, Gemma Moraga
Summary: The consumption of fruits and vegetables, such as persimmon, is crucial for human health due to their high content of bioactive compounds, fiber, minerals, and vitamins. Studies suggest that persimmon and its functional components can help prevent conditions like hyperlipidemia and hyperglycemia. This review focuses on the in vitro and in vivo digestibility of the main nutrients and bioactive compounds in persimmon, highlighting its potential as a recommended fruit for diet therapy.
Review
Biochemistry & Molecular Biology
Angela Inzulza-Tapia, Marcelo Alarcon
Summary: Cardiovascular diseases are the leading cause of death worldwide. Platelet-secreted non-coding RNA (ncRNA) play a crucial regulatory role in the occurrence and development of these diseases, and have potential value in identifying and treating cardiovascular diseases.
CURRENT MEDICINAL CHEMISTRY
(2022)
Article
Environmental Sciences
L. Morales-Quintana, D. Bustos, J. Gallego, O. Valdes, L. Guzman, F. M. Nachtigall, A. Marican, E. W. Hernandez-Rodriguez, F. Avila-Salas, W. Bueno-Silva, L. S. Santos, R. Castro
Summary: The study shows that melamine resin derivatives can effectively remove glyphosate from water as adsorbents, with adsorption efficiency comparable to activated carbon.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemical Research Methods
Ricardo J. Gonzalez, Cristina Quispe, Leonardo S. Santos, Fabiane M. Nachtigall
Summary: Organic gunshot residues (OGSRs) are important compounds used by forensic analysts to determine if a person has fired a firearm. A validation study was conducted to develop a new analysis method for identifying the main components of OGSRs. This research has significant implications for gunshot analysis in Chile.
JOURNAL OF MASS SPECTROMETRY
(2022)
Article
Health Care Sciences & Services
Ivan Palomo, Francisco Garcia, Cecilia Albala, Sergio Wehinger, Manuel Fuentes, Marcelo Alarcon, Diego Arauna, Hector Montecino, Diego Mendez, Magdalena Sepulveda, Peggy Fuica, Eduardo Fuentes
Summary: This study characterized the frailty syndrome in an older adult population using FTS-5, FTS-3, and Fried phenotype as diagnostic tools. The findings showed similar prevalence rates of frailty using these three tools, suggesting that FTS-3 could be a valuable tool for screening frailty in the community.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Developmental Biology
C. F. Burgos, R. Cikutovic, M. Alarcon
Summary: In this review, the role of miRNAs in male infertility pathology was analyzed, with a focus on identifying relevant biomarkers and potential therapeutic targets. By selecting and examining miRNAs with altered expressions in testis tissue, researchers were able to identify signaling pathways and protein interactions associated with male infertility, confirming the PI3K-Akt signaling pathway as the most affected and relevant pathway.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2022)
Article
Agronomy
Besma Kahlaoui, Javier Sanchez-Contreras, Leonardo S. Santos, Enrique Misle, Jose Antonio Yuri
Summary: The potential impact of preharvest environmental variation on the postharvest behavior of apples was evaluated in this study. It was found that there was significant variation in fruit parameters among different orchards, and these variations were correlated with preharvest environmental conditions. These findings highlight the importance of considering preharvest environmental factors in managing postharvest quality of apples, especially in the context of climate change.
NEW ZEALAND JOURNAL OF CROP AND HORTICULTURAL SCIENCE
(2022)
Article
Chemistry, Organic
Manda Sathish, Fabiane M. Nachtigall, Leonardo S. Santos
Summary: In this study, an efficient enantioselective imine reduction method was developed using in situ generated Fethiosquaramides catalysts (Fe-TSQs) 3a and 3b, resulting in the synthesis of chiral tetrahydro-beta-carbolines.
Article
Plant Sciences
Yasmina Chourak, El Hassan Belarbi, Tatiana Pagan Loeiro da Cunha-Chiamolera, Jose Luis Guil-Guerrero, Gilda Carrasco, Miguel Urrestarazu
Summary: This study evaluated the effect of electric conductivities on the production and quality of saffron grown in soilless culture. The best results were obtained with an EC range of 2.0 to 2.5 dS m(-1). Saffron quality in soilless culture improved slightly compared to traditional methods.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2022)
Article
Pharmacology & Pharmacy
Alfredo Pereira, Elizabeth Valdes-Munoz, Adolfo Marican, Gustavo Cabrera-Barjas, Sekar Vijayakumar, Oscar Valdes, Diana Rafael, Fernanda Andrade, Paulina Abaca, Daniel Bustos, Esteban F. Duran-Lara
Summary: Due to the growing bacterial resistance to antibiotics, there is a need for new antimicrobial treatment options. This study focused on the rational design of hydrogels as potential delivery systems for cationic antimicrobial peptides (cAMPs). The researchers used docking and Molecular Dynamics simulations to select the best hydrogel candidates based on their interaction with two types of cAMPs. The results showed that MN4-CM5-CL1 hydrogel (HG2) was the most promising candidate for future in vitro or in vivo experiments.
Review
Pharmacology & Pharmacy
Diana Rafael, Marcelo Guerrero, Adolfo Marican, Diego Arango, Bruno Sarmento, Roser Ferrer, Esteban F. Duran-Lara, Simon J. Clark, Simo Schwartz
Summary: Slow-release delivery systems are crucial for long-term sustained treatments of retinal diseases. Hydrogels, especially temperature-responsive hydrogels, have been studied as promising delivery vehicles for intravitreal injection of retinal therapies.
Article
Biochemistry & Molecular Biology
Andres Trostchansky, Marcelo Alarcon
Summary: Oxidative stress is involved in various non-communicable diseases, such as cardiovascular diseases. Excessive reactive oxygen species (ROS) formation can lead to the undesirable effects of oxidative stress. Platelets play a crucial role in arterial thrombosis, and excessive ROS formation stimulates platelet activation and aggregation. The proteins Protein Disulphide Isomerase (PDI) and NADPH oxidase (NOX) isoforms are involved in these processes. A bioinformatic analysis of their roles and interactions in platelets, as well as the signaling pathways involved, was performed. The data support the potential use of specific enzyme inhibitors or dual inhibition of these enzymes for treating diseases involving platelet dysfunction.
Article
Polymer Science
Moises A. Rojas, John Amalraj, Leonardo S. Santos
Summary: In this study, a two-step methodology for synthesizing small silver nanoparticles embedded into hydrogels based on chitosan and hydroxypropyl methylcellulose biopolymers is reported. The eco-friendly and cost-effective process uses d-glucose as an external green reducing agent and purified water as a solvent. Characterization of the silver nanocomposite hydrogels was performed through various techniques, and their mechanical and antibacterial properties were evaluated. The theoretical analyses provided insights into the unique structural properties of the prepared nano-scaled materials.
Article
Horticulture
Fernando Fuentes-Penailillo, Gilda Carrasco Silva, Ricardo Perez Guzman, Ignacio Burgos, Felipe Ewertz
Summary: The accelerated growth of computer vision techniques has allowed their application in various disciplines, including horticulture. In this study, an object detection model and a mobile application were developed that allowed seedlings to be counted from images.
Article
Horticulture
Carolina Seno Nascimento, Camila Seno Nascimento, Guilherme Lopes, Gilda Carrasco, Priscila Lupino Gratao, Arthur Bernardes Cecilio Filho
Summary: This study investigated the effect of selenium on the growth, yield, and biofortification of rocket plants. The results showed that selenium concentrations of 10-30 μM were beneficial for rocket plants, while concentrations above 50 μM were toxic.
