Article
Biochemistry & Molecular Biology
Eva A. Enyedy, Tatsiana Petrasheuskaya, Marton A. Kiss, Debora Wernitznig, Dominik Wenisch, Bernhard K. Keppler, Gabriella Spengler, Nora May, Eva Frank, Orsolya Domotor
Summary: The study investigated the solution chemical properties and biological activities of a novel tridentate salicyaldehyde semicarbazoneestrone hybrid and a related bicyclic compound. The compounds showed relatively high stability, efficient gallium binding, significant cytotoxicity against cancer cells, and dissociation at physiological pH.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Zohreh Razmara, Hojat Samareh Delarami, Vaclav Eigner, Michal Dusek
Summary: A new Bi(III) coordination compound, [Bi2(mu-ox)(dipic)2(taa)4].2H2O (1), has been synthesized and its structure was determined by SC-XRD analysis. The compound exhibits a di-nuclear structure with a distorted pentagonal-bipyramidal coordination environment around the Bi(III) center. Interaction analysis between the complex and the crystallized water molecules using Hirshfeld surface and two-dimensional fingerprint analysis revealed the significant contribution of O...H bonds. Quantum mechanical studies were conducted to understand the stability of the complex, which showed excellent antibacterial activity against Helicobacter pylori.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Anna A. Mukhacheva, Tatiana Asanova, Maxim R. Ryzhikov, Taisiya S. Sukhikh, Nikolay B. Kompankov, Vadim V. Yanshole, Alexey S. Berezin, Artem L. Gushchin, Pavel A. Abramov, Maxim N. Sokolov
Summary: The study found that Bi3+ and Pb2+ form stable complexes with [PW11O39](7-) anions, exhibiting stereochemically active lone pairs. Characterization revealed specific oxidation states and geometries for these complexes, along with photoluminescent properties.
DALTON TRANSACTIONS
(2021)
Article
Crystallography
Mezna Saleh Altowyan, Mostafa A. El-Naggar, Morsy A. M. Abu-Youssef, Saied M. Soliman, Matti Haukka, Assem Barakat, Ahmed M. A. Badr
Summary: A novel Ag(I) citrate complex with ethyl-3-quinolate (Et3qu) was synthesized and characterized. The complex exhibited broad-spectrum antimicrobial activity against A. fumigatus and demonstrated potent anticancer activity against breast and lung cancer cell lines.
Article
Chemistry, Inorganic & Nuclear
Zohreh Razmara, Cinthia Antunes Correa
Summary: A novel water-soluble inorganic complex of Cr(III) was synthesized and showed high efficiency in catalytic oxidation reactions, forming a 3D supramolecular network through hydrogen bonding.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Yong-Mei Chai, Hong-Bin Zhang, Xiao-Yi Zhang, Lan-Qin Chai
Summary: A novel complex was synthesized and characterized in this study. It exhibited diverse supramolecular structures and fluorescence behaviors, and showed antibacterial activity against Escherichia coli and Staphylococcus aureus.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Applied
Lijuan Hua, Wenge Li, Yan Chen, Kai Liang, He Cai, Jing Wang, Siyu Wang, Tianyue Yin, Lili Liang
Summary: The hexanuclear Nd (III) complex exhibits promising antitumor and antifungal activities, with a trinuclear cluster structure and high inhibition rates against human hepatocellular carcinoma and Candida albicans.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Zouhaier Aloui, Chayma Ounelli, Manel Essid, Francesco Nicolo, Giovanni Bella, Antonio Santoro, Sonia Abid, G. Bruno
Summary: This paper reports the synthesis, structural characterization, Infrared spectroscopy and optical properties of a new chlorobismuthate(III) hybrid compound. The compound contains discrete binuclear Bi2Cl11 and mononuclear BiCl6 anions coexisting in the same structure with a 1-(2-pyridyl)piperazine-based ligand. The structure of the compound was determined by single-crystal X-ray diffraction, and the vibrational spectrum measured by FT-IR spectroscopy confirmed the presence of an organic cation at room temperature.
JOURNAL OF SOLID STATE CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Ziyan Lv, Rukang Li
Summary: In this study, a tantalum phosphate crystal Na11Ta8P7O43 with a moderate second harmonic response was synthesized using self-fluxes method. The crystal was found to have unique structural features and moderate nonlinear effects. It exhibits phase-matchable second harmonic generation, a shorter cutoff edge than known materials LiTaO3 and KTiOPO4, and high transmittance in the visible to near infrared band, suggesting its potential as a nonlinear optical crystal.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Ziyan Lv, Rukang Li
Summary: In this study, a tantalum phosphate crystal with a moderate second harmonic response and unique structural features was successfully synthesized. It has the potential to serve as a nonlinear optical crystal.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Jiahui Wu, Linan Miao, Mingming Yang, Ang Li, Yan Cao, Qiyu Wang, Jiahui Zhang, Zhonglu You
Summary: Two new molybdenum complexes, [MoO2L1] and [MoO2L2], were synthesized by reacting bis(acetylacetonato)dioxomolybdenum(VI) with 4-fluoro-2-((pyridin-2-ylmethylene)amino)phenol and 3-methyl-2-((pyridin-2-ylmethylene)amino)phenol in methanol. The complexes were characterized by various spectroscopic techniques and their molecular structures were determined by X-ray crystallography. The complexes exhibited interesting antibacterial and antifungal activities when tested against different strains.
INORGANICA CHIMICA ACTA
(2023)
Article
Multidisciplinary Sciences
Mezna Saleh Altowyan, Saied M. Soliman, Dhuha Al-Wahaib, Assem Barakat, Ali Eldissouky Ali, Hemmat A. Elbadawy
Summary: A new Ag(I)-azine complex was synthesized and characterized, showing antimicrobial, antioxidant, and cytotoxic activities. The presence of azine molecules in the complex affects its biological actions.
Article
Chemistry, Inorganic & Nuclear
Saied M. Soliman, Eman M. Fathalla, Mona M. Sharaf, Ayman El-Faham, Assem Barakat, Matti Haukka, Alexandra M. Z. Slawin, John Derek Woollins, Morsy A. M. Abu-Youssef
Summary: This article introduces a new Co(II) perchlorate complex with the ligand 4,4'-(6-(1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine (BMBIT). The structure of the complex is confirmed using single-crystal X-ray diffraction. The complex has distorted octahedral coordination geometry with two BMBIT ligand units and four water molecules as monodentate ligands. The complex exhibits good antifungal activity and broad spectrum antimicrobial action.
Article
Chemistry, Organic
Marie Pascaline Rahelivao, Ingmar Bauer, Tilo Luebken, Olga Kataeva, Anne Vehlow, Nils Cordes, Hans-Joachim Knoelker
Summary: The relative configuration of the marine sesquiterpenoid oxyfungiformin, isolated from the soft coral Capnella fungiformis, was confirmed by synthesis and comparison of values for optical rotation. The cytotoxic activity of oxyfungiformin and a diastereoisomer was observed in lung, breast, and cervical cancer cells.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Materials Science, Ceramics
M. Cabral, A. P. Brown, J. Bultitude, A. Britton, R. Brydson, T. Roncal-Herrero, D. A. Hall, S. J. Milne, A. M. Rappe, D. C. Sinclair, J. Zhang, Y. Li
Summary: Aberration corrected scanning transmission electron microscopy (STEM) has been used to reveal local structure and nano-chemistry in a Ca modified BaTiO3-Bi(Mg0.5Ti0.5)O3 relaxor dielectric ceramic, indicating the presence of nanopolar clusters and high levels of Bi vacancies in the matrix. This suggests that A-site vacancies may modulate the nanopolar structure and promote flattening of the permittivity-temperature response in this class of dielectrics.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2023)
Article
Biochemistry & Molecular Biology
Geisa Gabriela da Silva, Lucia Pinheiro Santos Pimenta, Julio Onesio Ferreira Melo, Henrique de Oliveira Prata Mendonca, Rodinei Augusti, Jacqueline Aparecida Takahashi
Summary: This study evaluated the potential of avocado peel and seed extracts as sources of neuroprotective compounds. The extracts were found to be rich in minerals, phenolic compounds, and flavonoids, and exhibited good antioxidant activity. Among them, the ethanolic peel extract showed the best acetylcholinesterase inhibitory activity, while the ethanolic seed extract demonstrated significant neuroprotective effects.
Article
Biochemistry & Molecular Biology
Antonio Henrique de Souza, Henrique de Oliveira Prata Mendonca, Ana Cardoso Clemente Filha Ferreira de Paula, Rodinei Augusti, Camila Argenta Fante, Julio Onesio Ferreira Melo, Lanamar de Almeida Carlos
Summary: This study evaluated the physicochemical characteristics and production of bioactive compounds of Pereskia aculeata Mill. at different harvest times. The results showed that the chemical profile was affected only when harvested in winter, while it remained stable in other seasons. There was no difference in the production of bioactive compounds and antioxidant activity between seasons, while brightness, chroma, and leaf pH remained constant.
Article
Biochemistry & Molecular Biology
Ana Luiza Coeli Cruz Ramos, Laiza Andrade Nogueira, Mauro Ramalho Silva, Ana Carolina do Carmo Mazzinghy, Ana Paula Xavier Mariano, Tassia Nunes de Albuquerque Rodrigues, Ana Cardoso Clemente Filha Ferreira de Paula, Angelita Cristine de Melo, Rodinei Augusti, Raquel Linhares Bello de Araujo, Inayara Cristina Alves Lacerda, Julio Onesio Ferreira Melo
Summary: This study aimed to evaluate the efficiency of different SPME fibers in the extraction of volatile organic compounds from grumixama pulp and optimize the extraction method. By using solid-phase microextraction, the characteristic volatile profile of grumixama was determined, and it was found that DVB/CAR/PDMS fiber showed better efficiency.
Article
Biochemistry & Molecular Biology
Jose A. F. de Oliveira, Geovana G. Terra, Thiago G. Costa, Bruno Szpoganicz, Priscila P. Silva-Caldeira, Ivina P. de Souza, Elene C. Pereira-Maia, Adailton J. Bortoluzzi
Summary: A new cis-dihalo copper(II) complex has been synthesized and characterized. The complex showed inhibitory effect on the growth of myelogenous leukemia cells.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Vania de Lourdes G. Teles, Pedro Henrique Vendramini, Rodinei Augusti, Leticia M. Costa
Summary: Basil samples were analyzed using desorption electrospray ionization mass spectrometry imaging (DESI-MSI) to identify amino acids and sugars. The study found that basil leaves accumulated various amino acids and sugars as a defense mechanism against cadmium contamination. The results demonstrated the potential of DESI-MSI as a valuable tool for metabolomics studies in plants exposed to toxic metals.
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Editorial Material
Chemistry, Analytical
Rodinei Augusti
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Ivina P. de Souza, Ariane C. C. de Melo, Bernardo L. Rodrigues, Adailton Bortoluzzi, Simon Poole, Zara Molphy, Vickie McKee, Andrew Kellett, Rodrigo B. Fazzi, Ana M. da Costa Ferreira, Elene C. Pereira-Maia
Summary: Five ternary copper(II) complexes were synthesized and characterized. Two complexes showed strong anti-cancer activity and DNA cleavage ability.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Vinicius Tadeu da Veiga Correia, Viviane Dias Medeiros Silva, Henrique de Oliveira Prata Mendonca, Ana Luiza Coeli Cruz Ramos, Mauro Ramalho Silva, Rodinei Augusti, Ana Cardoso Clemente Filha Ferreira de Paula, Ricardo Manuel de Seixas Boavida Ferreira, Julio Onesio Ferreira Melo, Camila Argenta Fante
Summary: This study determined the chemical profiles of jabuticaba and jambolan fruits using paper spray mass spectrometry and found that they are rich in phenolic compounds. The different parts of the fruits produced different chemical fingerprints when extracted using different solvents. These compounds in jabuticaba and jambolan have the potential to positively impact human health and nutrition.
Article
Biochemistry & Molecular Biology
Maria Clara Coutinho Macedo, Vinicius Tadeu da Veiga Correia, Viviane Dias Medeiros Silva, Debora Tamires Vitor Pereira, Rodinei Augusti, Julio Onesio Ferreira Melo, Christiano Vieira Pires, Ana Cardoso Clemente Filha Ferreira de Paula, Camila Argenta Fante
Summary: In this study, yellow passion fruit peel flour was developed and evaluated for its characteristics, including physicochemical, microscopic, colorimetric, and granulometric properties, as well as its content of phenolic compounds and carotenoids, and antioxidant capacity. The analysis revealed that the flour had a light color, heterogeneous granulometry, and high content of carbohydrates, carotenoids, and phenolic compounds with strong antioxidant capacity. The presence of various beneficial compounds was identified through analytical techniques. The findings highlight the potential of yellow passion fruit peel flour as a food ingredient, offering advantages such as waste reduction, contribution to sustainability, and enhancement of functional properties in food products. Its high content of bioactive compounds also provides health benefits to consumers.
Article
Biochemistry & Molecular Biology
Maria Clara Coutinho Macedo, Viviane Dias Medeiros Silva, Mateus Sa Magalhaes Serafim, Vinicius Tadeu da Veiga Correia, Debora Tamires Vitor Pereira, Patricia Regina Amante, Antonio Soares Junior da Silva, Henrique de Oliveira Prata Mendonca, Rodinei Augusti, Ana Cardoso Clemente Filha Ferreira de Paula, Julio Onesio Ferreira Melo, Christiano Vieira Pires, Camila Argenta Fante
Summary: This study investigated the effects of different ultrasonic extraction times on the phytochemical profile, antioxidant and antibacterial activities of ethanolic extracts from the leaves of Pereskia aculeata Miller. The results showed that the extraction times influenced the phenolic content and antioxidant activity of the extracts. All of the extracts inhibited the growth of Staphylococcus aureus, and chlorogenic acid was the primary compound detected. This study provides insights into the potential use of P. aculeata leaves and their extract in the food and pharmaceutical industries.
Article
Biochemical Research Methods
Ana Gabriella Carvalho Miguita, Rodinei Augusti, Marcelo Martins Sena, Clesia Cristina Nascentes
Summary: This study analyzed 43 commercially acquired samples of St. John's wort using paper spray ionization mass spectrometry (PS-MS). It was found that 52.3% of the samples were adulterated with other plant species, including Ageratum conyzoides and Senna spectabilis. Only 13 out of 35 samples produced in Brazil were deemed authentic. Therefore, there is a clear need to improve the quality control of these drugs in Brazil.
JOURNAL OF MASS SPECTROMETRY
(2023)
Article
Biochemical Research Methods
Larissa Batista dos Santos, Diego Magalhaes Costa, Mariana Ramos Almeida, Rodinei Augusti
Summary: In this paper, the researchers used sandpaper as a tool to analyze polishable solid samples. They demonstrated the feasibility of this method by sanding the surface of coffee beans and obtaining fingerprints using mass spectrometry. The new technique, named sandpaper spray mass spectrometry (SPS-MS), has advantages over traditional paper spray mass spectrometry in analyzing polishable solid samples and offers a more straightforward approach for analyzing hard surfaces such as wood, plastic, and crop grains.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Review
Biochemistry & Molecular Biology
Jania dos Santos Rosario, Fabio Henrique Moreira, Lara Hewilin Fernandes Rosa, Wendell Guerra, Priscila Pereira Silva-Caldeira
Summary: Bismuth-based drugs are used to treat ulcers and gastrointestinal ailments, and their synergistic activity with antibiotics makes them ideal for multiple therapy regimens. These compounds have low cost, are safe for human use, and have potential against various diseases. However, their limited bioavailability in physiological environments necessitates the development of new bismuth compounds. This review focuses on recent updates in bismuth compounds, particularly those with potent activity and low toxicity, in order to rationalize the development of new bismuth-based drugs.
Article
Environmental Sciences
Ricardo Mathias Orlando, Rodinei Augusti, Adriana Nori de Macedo, Mariana Ramos Almeida, Zenilda de Lourdes Cardeal, Helvecio C. Menezes, Claudia Carvalhinho Windmoeller, Cyntia Cabral Ribeiro, Millena Christie Ferreira Avelar, Marina Caneschi de Freitas, Lucas Pinto da Silva, Jose Messias Gomes, Julia Celia Lima Gomes, Julia Vasconcellos Augusti, Barbara Oliveira Lopes, Nathalia de Oliveira Melo, Luciene Paiva Moreira da Silva, Denise Versiane Monteiro de Sousa
Summary: This manuscript presents a novel and simple strategy for optimizing the determination of contaminants in groundwater. The strategy utilizes online solid-phase extraction (SPE) coupled with ultrahigh-performance liquid chromatography (UHPLC) and tandem mass spectrometry (MS/MS). Various factors were considered during the methodology optimization process, including analyte sorption, cleanup conditions, injection volume, and matrix effects. Matrix effects were mitigated by adding additives (citric acid and hydroxylamine) directly into the groundwater samples. The optimized conditions yielded excellent results for evaluating ten contaminants, even without internal standards, highlighting the importance of investigating experimental issues in analytical protocols. This work provides valuable insights for researchers working on LC-MS/MS methods for determining organic contaminants in groundwater.
Article
Chemistry, Inorganic & Nuclear
Ivina P. de Souza, Julia R. L. Silva, Amanda O. Costa, Jennifer T. J. Freitas, Renata Diniz, Rodrigo B. Fazzi, Ana M. da Costa Ferreira, Elene C. Pereira-Maia
Summary: Two ternary copper(II) complexes were synthesized and characterized. The complexes were found to bind to DNA, capable of cleaving DNA and inhibiting tumor cell growth.
