Recent Syntheses of 1,2,3,4-Tetrahydroquinolines, 2,3-Dihydro-4(1H)-quinolinones and 4(1H)-Quinolinones using Domino Reactions

Ivacaftor

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Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase

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N-Aryl-6-methoxy-1,2,3,4-tetrahydroquinolines: A novel class of antitumor agents targeting the colchicine site on tubulin

(2013) Xiao-Feng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinolone alkaloids with antibacterial and cytotoxic activities from the fruits of Evodia rutaecarpa

(2013) Xiao-Xia Wang et al.   FITOTERAPIA

Substituted 4-Oxo-1,2,3,4-tetrahydroquinoline-3-carboxylic Esters by a Tandem Imine Addition-SNAr Reaction

(2013) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and Pharmacological Profiling of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) as Allosteric Modulators of the M1 Muscarinic Receptor

(2013) Shailesh N. Mistry et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aromatic Sulfonamides Containing a Condensed Piperidine Moiety as Potential Oxidative Stress-Inducing Anticancer Agents

(2013) Ramóna Madácsi et al.   Medicinal Chemistry

The Evolution of Drugs on Schistosoma Treatment: Looking to the Past to Improve the Future

(2013) Maira Galdino da Rocha Pitta et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Ru-Catalyzed Synthesis of Dihydrofuroquinolines from Azido-cyclopropyl Ketones

(2013) Weijun Yang et al.   ORGANIC LETTERS

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

(2013) A. Nilsen et al.   Science Translational Medicine

Antifungal Activity of Tetrahydroquinolines against Some Phytopathogenic Fungi

(2013) Margarita Gutiérrez et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

Design and Synthesis of Aza-Flavones as a New Class of Xanthine Oxidase Inhibitors

(2012) Rajni Dhiman et al.   ARCHIV DER PHARMAZIE

Design and synthesis of new tetrahydroquinolines derivatives as CETP inhibitors

(2012) Ana Escribano et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New cytotoxic quinolone alkaloids from fruits of Evodia rutaecarpa

(2012) Xin Huang et al.   FITOTERAPIA

Per-6-amino-β-cyclodextrin as a Chiral Base Catalyst Promoting One-Pot Asymmetric Synthesis of 2-Aryl-2,3-dihydro-4-quinolones

(2012) Kuppusamy Kanagaraj et al.   JOURNAL OF ORGANIC CHEMISTRY

Construction of Nitrogen-Fused Tetrahydroquinolines via a Domino Reaction

(2012) Nicolas Gigant et al.   ORGANIC LETTERS

Synthesis of 2,3-Dihydro-4(1H)-quinolones and the Corresponding 4(1H)-Quinolones via Low-Temperature Fries Rearrangement of N-Arylazetidin-2-ones

(2011) Jens Lange et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists

(2011) Robert G. Schmidt et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle

(2011) Srivari Chandrasekhar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Advances in the Chemistry of Tetrahydroquinolines

(2011) Vellaisamy Sridharan et al.   CHEMICAL REVIEWS

Enantioselective Syntheses of Tetrahydroquinolines Based on Iridium-Catalyzed Allylic Substitutions: Total Syntheses of (+)-Angustureine and (-)-Cuspareine

(2011) Gedu Satyanarayana et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

(±)-2-Aryl-2,3-dihydro-4(1H)-quinolinones by a tandem reduction-Michael addition reaction

(2011) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

A novel ionic liquid mediated synthesis of 4(1H)-quinolones, 5H-thiazolo[3,2-a]pyrimidin-5-one and 4H-pyrimido[2,1-b]benzothiazol-4-ones

(2011) Ashok K. Yadav et al.   TETRAHEDRON LETTERS

[Fe(F20TPP)Cl] catalyzed intramolecular C–N bond formation for alkaloid synthesis using aryl azides as nitrogen source

(2010) Yungen Liu et al.   CHEMICAL COMMUNICATIONS

Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects

(2010) Prabodh Chander Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ester- and ketone-substituted (±)-1-alkyl-6-nitro-1,2,3,4-tetrahydroquinolines by a tandem SNAr-Michael reaction

(2010) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Efficient Entry into 2-Substituted Tetrahydroquinoline Systems through Alkylative Ring Expansion: Stereoselective Formal Synthesis of (±)-Martinellic Acid

(2010) Masafumi Ueda et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of 2-Aryl-2,3-dihydro-4-quinolones via Bifunctional Thiourea-Mediated Intramolecular Cyclization

(2010) Xiaoqian Liu et al.   ORGANIC LETTERS

6-Nitro-1,2,3,4-tetrahydroquinoline-4-carboxylic Esters and 7-Nitro-3,4-dihydroquinoxaline- 1(2H)-carboxylic Esters by a Tandem Reductive Amination-SNAr Reaction

(2010) Richard A. Bunce et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

4(1H)-Quinolinones by a Tandem Reduction-Addition-Elimination Reaction

(2010) Richard A. Bunce et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

Cytochrome P450 2D6 inhibitory constituents of Lunasia amara

(2010) Subehan et al.   Phytochemistry Letters

Hydrogenation of ortho-nitrochalcones over Pd/C as a simple access to 2-substituted 1,2,3,4-tetrahydroquinolines

(2010) Angela Patti et al.   TETRAHEDRON

Heterogeneous metallo-organocatalysis for the selective one-pot synthesis of 2-benzylidene-indoxyl and 2-phenyl-4-quinolone

(2010) Marie Genelot et al.   TETRAHEDRON

Optimised procedures for the one-pot selective syntheses of indoxyls and 4-quinolones by a carbonylative Sonogashira/cyclisation sequence

(2009) Marie Genelot et al.   APPLIED CATALYSIS A-GENERAL

Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants

(2009) Dai-Shi Su et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists

(2009) Jack D. Scott et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The methods of synthesis, modification, and biological activity of 4-quinolones (review)

(2009) A. A. Boteva et al.   Chemistry of Heterocyclic Compounds

Recent Advances in the Synthesis of Indole and Quinoline Derivatives through Cascade Reactions

(2009) José Barluenga et al.   Chemistry-An Asian Journal

The 4-Quinolone-3-Carboxylic Acid Motif as a Multivalent Scaffold in Medicinal Chemistry

(2009) Claudia Mugnaini et al.   CURRENT MEDICINAL CHEMISTRY

Benzo-fused heterocycles and carbocycles by intramolecular SNAr and tandem SN2-SNAr reactions

(2009) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

6-Nitro-1,2,3,4-tetrahydroquinolines by a tandem reductive amination-SNAr reaction

(2009) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

1-Alkyl-2,3-dihydro-4(1H)-quinolinones by a tandem Michael-SNAr annulation reaction

(2009) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Divergent reactivity in tandem reduction-Michael ring closures of five- and six-membered cyclic enones

(2009) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Quinolone Carboxylic Acids as a Novel Monoketo Acid Class of Human Immunodeficiency Virus Type 1 Integrase Inhibitors

(2009) Motohide Sato et al.   JOURNAL OF MEDICINAL CHEMISTRY

3-Hydroxy-2-phenyl-4(1H)-quinolinones as Promising Biologically Active Compounds

(2009) P. Hradil et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Synthesis of a quinolone library from ynones

(2009) Timothy R. Ward et al.   TETRAHEDRON LETTERS