Design and Synthesis of a Series of Pyrido[2,3-d]pyrimidine Derivatives as CCR4 Antagonists

An Antagonist for CCR4 Alleviates Murine Allergic Rhinitis by Intranasal Administration

(2012) Hui Qi et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

CC Chemokine Receptor 4 Contributes to Innate NK and Chronic Stage T Helper Cell Recall Responses during Mycobacterium bovis Infection

(2011) Valerie R. Stolberg et al.   AMERICAN JOURNAL OF PATHOLOGY

Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients

(2010) P. Vijayanand et al.   JOURNAL OF IMMUNOLOGY

Discovery and Optimization of Novel 3-Piperazinylcoumarin Antagonist of Chemokine-like Factor 1 with Oral Antiasthma Activity in Mice

(2010) Gang Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation

(2009) F. Perros et al.   ALLERGY

Potent and orally bioavailable CCR4 antagonists: Synthesis and structure–activity relationship study of 2-aminoquinazolines

(2008) Kazuhiro Yokoyama et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Two C-terminal peptides of human CKLF1 interact with the chemokine receptor CCR4

(2007) Ying Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY