Journal
MOLECULES
Volume 16, Issue 7, Pages 6060-6067Publisher
MDPI AG
DOI: 10.3390/molecules16076060
Keywords
feeding deterrents; Ceriops tagal; Tribolium castaneum; tagalsin
Funding
- National New-drug Innovation Project [2009ZX09501-014]
- Hi-Tech Research and Development of China [2006AA10A209]
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The screening of several Chinese mangrove plants for insecticidal principles showed that ethanol extract of Ceriops tagal stems and twigs possessed significant feeding deterrent activity against the red flour beetle, Tribolium castaneum (Family: Rhizophoraceae). From the ethanol extract, three feeding deterrent diterpenoids were isolated by bioassay-guided fractionation. The compounds were identified as tagalsin A, B, and H on the basis of their phytochemical and spectral data. Tagalsin A, B, and H exhibited strong feeding deterrent activity against T. castaneum adults with EC50 values of 375.3 ppm, 277.3 ppm, and 285.45 ppm, respectively.
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