Journal
MOLECULES
Volume 15, Issue 11, Pages 8251-8259Publisher
MDPI
DOI: 10.3390/molecules15118251
Keywords
Eremochloa ophiuroides; C-glycosidic flavones; obesity; pancreatic lipase
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Activity-guided fractionation of a methanolic extract of the leaves of Eremochloa ophiuroides (centipede grass) using a pancreatic lipase inhibitory assay led to the isolation and identification of a new C-glycosidic flavone, luteolin 6-C-beta-D-boivinopyranoside (1), as well as eight known compounds. The structures of these compounds were established on the basis of interpretation of their spectroscopic data. Among these isolates, the C-glycosidic flavones 1-5 showed potent inhibitory effects on pancreatic lipase, with IC50 values ranging from 18.5 +/- 2.6 to 50.5 +/- 3.9 mu M.
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