4.6 Article

A convenient synthesis of amino acid methyl esters

Journal

MOLECULES
Volume 13, Issue 5, Pages 1111-1119

Publisher

MDPI
DOI: 10.3390/molecules13051111

Keywords

amino acid methyl ester hydrochlorides; amino acids; trimethylchlorosilane; esterification

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A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.

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