Properties of cell death models calibrated and compared using Bayesian approaches

Exploring the Contextual Sensitivity of Factors that Determine Cell-to-Cell Variability in Receptor-Mediated Apoptosis

(2012) Suzanne Gaudet et al.   PLoS Computational Biology

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Rapid Phospho-Turnover by Receptor Tyrosine Kinases Impacts Downstream Signaling and Drug Binding

(2011) Laura B. Kleiman et al.   MOLECULAR CELL

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

(2011) B. B. Aldridge et al.   Molecular Systems Biology

Separating intrinsic from extrinsic fluctuations in dynamic biological systems

(2011) A. Hilfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Classic and contemporary approaches to modeling biochemical reactions

(2010) W. W. Chen et al.   GENES & DEVELOPMENT

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells

(2010) Leo Neumann et al.   Molecular Systems Biology

Still embedded together binding to membranes regulates Bcl-2 protein interactions

(2010) B Leber et al.   ONCOGENE

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

Inferring Signaling Pathway Topologies from Multiple Perturbation Measurements of Specific Biochemical Species

(2010) T.-R. Xu et al.   Science Signaling

Bistability in Apoptosis by Receptor Clustering

(2010) Kenneth L. Ho et al.   PLoS Computational Biology

Parameter Estimation and Model Selection in Computational Biology

(2010) Gabriele Lillacci et al.   PLoS Computational Biology

An empirical Bayesian approach for model-based inference of cellular signaling networks

(2009) David J Klinke   BMC BIOINFORMATICS

Dynamics of outer mitochondrial membrane permeabilization during apoptosis

(2009) M Rehm et al.   CELL DEATH AND DIFFERENTIATION

Estimating Bayes factors via thermodynamic integration and population MCMC

(2009) Ben Calderhead et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

Understanding apoptosis by systems biology approaches

(2009) Inna N. Lavrik et al.   Molecular BioSystems

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

(2009) William W Chen et al.   Molecular Systems Biology

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model

(2009) Samuel Bandara et al.   PLoS Computational Biology

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

(2008) Jonathan F. Lovell et al.   CELL

Sloppiness, robustness, and evolvability in systems biology

(2008) Bryan C Daniels et al.   CURRENT OPINION IN BIOTECHNOLOGY

Integrating Computational and Biochemical Studies to Explore Mechanisms in NF-κB Signaling

(2008) Jeffrey D. Kearns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marginal likelihood estimation via power posteriors

(2008) N. Friel et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL

Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death

(2008) John G Albeck et al.   PLOS BIOLOGY

A Dual Receptor Crosstalk Model of G-Protein-Coupled Signal Transduction

(2008) Patrick Flaherty et al.   PLoS Computational Biology