Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

(2012) Vladimir Litvak et al.   NATURE

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

(2012) Karen Adelman et al.   NATURE REVIEWS GENETICS

The PKB/FOXO switch in aging and cancer

(2011) David E.A. Kloet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hippo/Mst1 Stimulates Transcription of the Proapoptotic Mediator NOXA in a FoxO1-Dependent Manner

(2011) K. Valis et al.   CANCER RESEARCH

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

(2011) E C Ferber et al.   CELL DEATH AND DIFFERENTIATION

The complex transcription regulatory landscape of our genome: control in three dimensions

(2011) Erik Splinter et al.   EMBO JOURNAL

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

(2011) E. Splinter et al.   GENES & DEVELOPMENT

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Mammalian Target of Rapamycin Complex 2 (mTORC2) Negatively Regulates Toll-like Receptor 4-mediated Inflammatory Response via FoxO1

(2011) Jonathan Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

(2011) N. Alic et al.   Molecular Systems Biology

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

(2011) Xin Zhang et al.   NATURE CELL BIOLOGY

Enhancer function: new insights into the regulation of tissue-specific gene expression

(2011) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes

(2011) Michal Mokry et al.   NUCLEIC ACIDS RESEARCH

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

(2011) V M Renault et al.   ONCOGENE

Transcription Factors E2A, FOXO1 and FOXP1 Regulate Recombination Activating Gene Expression in Cancer Cells

(2011) Zhengshan Chen et al.   PLoS One

The Extending Network of FOXO Transcriptional Target Genes

(2010) Kristan E. van der Vos et al.   ANTIOXIDANTS & REDOX SIGNALING

Integrating Opposing Signals Toward Forkhead Box O

(2010) Maaike C.W. van den Berg et al.   ANTIOXIDANTS & REDOX SIGNALING

Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation

(2010) Sergei Nechaev et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

c-Myc Regulates Transcriptional Pause Release

(2010) Peter B. Rahl et al.   CELL

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

(2010) WuQiang Fan et al.   EMBO JOURNAL

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

(2010) Eugene Schuster et al.   Molecular Systems Biology

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Efficient Double Fragmentation ChIP-seq Provides Nucleotide Resolution Protein-DNA Binding Profiles

(2010) Michal Mokry et al.   PLoS One

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

(2010) Francesca De Santa et al.   PLOS BIOLOGY

Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1

(2009) M. Hatta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

(2009) M. Hoogenkamp et al.   BLOOD

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Genomic interactions: Chromatin loops and gene meeting points in transcriptional regulation

(2009) Tom Sexton et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging

(2008) K. Miyamoto et al.   BLOOD

Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFκB transcription factors

(2008) Jolyon Terragni et al.   BMC CELL BIOLOGY

FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

(2008) Mathieu Lupien et al.   CELL

Nutritional Control of Protein Biosynthetic Capacity by Insulin via Myc in Drosophila

(2008) Aurelio A. Teleman et al.   Cell Metabolism

FOXO3A Regulates Peroxiredoxin III Expression in Human Cardiac Fibroblasts

(2008) Calin B. Chiribau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo3 Is Essential for the Regulation of Ataxia Telangiectasia Mutated and Oxidative Stress-mediated Homeostasis of Hematopoietic Stem Cells

(2008) Safak Yalcin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Forkhead Transcription Factor FOXO3a Increases Phosphoinositide-3 Kinase/Akt Activity in Drug-Resistant Leukemic Cells through Induction of PIK3CA Expression

(2008) R. C.-Y. Hui et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated software system for analyzing ChIP-chip and ChIP-seq data

(2008) Hongkai Ji et al.   NATURE BIOTECHNOLOGY

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

Forkhead transcription factors and ageing

(2008) L Partridge et al.   ONCOGENE

FOXO-binding partners: it takes two to tango

(2008) K E van der Vos et al.   ONCOGENE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

Unravelling the tumor-suppressive functions of FOXO proteins

(2008) Tobias B. Dansen et al.   TRENDS IN CELL BIOLOGY