Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression

Paternal Age at Childbearing and Offspring Psychiatric and Academic Morbidity

(2014) Brian M. D’Onofrio et al.   JAMA Psychiatry

Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels

(2013) Timothy G. Jenkins et al.   FERTILITY AND STERILITY

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia

(2013) S. Kohl et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Parental olfactory experience influences behavior and neural structure in subsequent generations

(2013) Brian G Dias et al.   NATURE NEUROSCIENCE

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa

(2013) Serap Erkek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Paternal Age Effect Mutations and Selfish Spermatogonial Selection: Causes and Consequences for Human Disease

(2012) Anne Goriely et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Role of CpG context and content in evolutionary signatures of brain DNA methylation

(2012) Yurong Xin et al.   Epigenetics

Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: implications for neuropsychiatric disease

(2012) R G Smith et al.   MOLECULAR PSYCHIATRY

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Methyl-Analyzer—whole genome DNA methylation profiling

(2011) Yurong Xin et al.   BIOINFORMATICS

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

(2011) Emma L. Dempster et al.   HUMAN MOLECULAR GENETICS

High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: A putative model for ART-conceived humans

(2011) Lei Li et al.   REPRODUCTIVE TOXICOLOGY

New Perspectives on Rodent Models of Advanced Paternal Age: Relevance to Autism

(2011) Claire J. Foldi et al.   Frontiers in Behavioral Neuroscience

Chromatin Organization in Sperm May Be the Major Functional Consequence of Base Composition Variation in the Human Genome

(2011) Tanya Vavouri et al.   PLoS Genetics

Increased de novo copy number variants in the offspring of older males

(2011) T Flatscher-Bader et al.   Translational Psychiatry

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Advanced paternal age is associated with alterations in discrete behavioural domains and cortical neuroanatomy of C57BL/6J mice

(2010) Claire J. Foldi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

(2010) AnhThu Nguyen et al.   FASEB JOURNAL

Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns

(2010) J. R. Edwards et al.   GENOME RESEARCH

Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies

(2010) C M Hultman et al.   MOLECULAR PSYCHIATRY

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model

(2009) Rebecca G. Smith et al.   PLoS One

Change in maternal environment induced by cross-fostering alters genetic and epigenetic effects on complex traits in mice

(2009) R. Hager et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Advancing Paternal Age and Bipolar Disorder

(2008) Emma M. Frans et al.   ARCHIVES OF GENERAL PSYCHIATRY

Long-Term Effects of Delayed Fatherhood in Mice on Postnatal Development and Behavioral Traits of Offspring1

(2008) Silvia García-Palomares et al.   BIOLOGY OF REPRODUCTION

Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis

(2008) M. R. Branco et al.   GENES & DEVELOPMENT

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1

(2008) Marjolijn J L Ligtenberg et al.   NATURE GENETICS

Realistic expectations of prepulse inhibition in translational models for schizophrenia research

(2008) Neal R. Swerdlow et al.   PSYCHOPHARMACOLOGY