Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays

(2013) G. Costain et al.   HUMAN MOLECULAR GENETICS

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Assessing Methods for Assigning SNPs to Genes in Gene-Based Tests of Association Using Common Variants

(2013) Ashley Petersen et al.   PLoS One

A Genetic Deconstruction of Neurocognitive Traits in Schizophrenia and Bipolar Disorder

(2013) Carla P. D. Fernandes et al.   PLoS One

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

(2013) D. T. Balu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific Glial Functions Contribute to Schizophrenia Susceptibility

(2013) A. Goudriaan et al.   SCHIZOPHRENIA BULLETIN

Synaptopathies: diseases of the synaptome

(2012) Seth GN Grant   CURRENT OPINION IN NEUROBIOLOGY

Common variant at 16p11.2 conferring risk of psychosis

(2012) S Steinberg et al.   MOLECULAR PSYCHIATRY

De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

(2012) Bin Xu et al.   NATURE GENETICS

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

(2012) Jess Nithianantharajah et al.   NATURE NEUROSCIENCE

Partitioning the Proteome: Phase Separation for Targeted Analysis of Membrane Proteins in Human Post-Mortem Brain

(2012) Jane A. English et al.   PLoS One

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

(2012) Àlex Bayés et al.   PLoS One

Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

(2012) P H Lee et al.   Translational Psychiatry

Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

(2012) R Belzeaux et al.   Translational Psychiatry

Common Proteomic Changes in the Hippocampus in Schizophrenia and Bipolar Disorder and Particular Evidence for Involvement of Cornu Ammonis Regions 2 and 3

(2011) Melanie Föcking et al.   ARCHIVES OF GENERAL PSYCHIATRY

Stimulus-Selective Response Plasticity in the Visual Cortex: An Assay for the Assessment of Pathophysiology and Treatment of Cognitive Impairment Associated with Psychiatric Disorders

(2011) Sam F. Cooke et al.   BIOLOGICAL PSYCHIATRY

Anti-NMDA receptor encephalitis: an important differential diagnosis in psychosis

(2011) Helen Barry et al.   BRITISH JOURNAL OF PSYCHIATRY

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

A Versatile Gene-Based Test for Genome-wide Association Studies

(2010) Jimmy Z. Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Markers of Glutamate Synaptic Transmission and Plasticity Are Increased in the Anterior Cingulate Cortex in Bipolar Disorder

(2010) Sharon L. Eastwood et al.   BIOLOGICAL PSYCHIATRY

The Neuroproteomics of Schizophrenia

(2010) Jane A. English et al.   BIOLOGICAL PSYCHIATRY

Myelin matters: proteomic insights into white matter disorders

(2010) Hauke B Werner et al.   Expert Review of Proteomics

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Evidence for Abnormal Forward Trafficking of AMPA Receptors in Frontal Cortex of Elderly Patients with Schizophrenia

(2010) John C Hammond et al.   NEUROPSYCHOPHARMACOLOGY

Expression of the NR2B-NMDA receptor subunit and its Tbr-1/CINAP regulatory proteins in postmortem brain suggest altered receptor processing in schizophrenia

(2010) Lars V. Kristiansen et al.   SYNAPSE

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

SnapShot: Endocytic Trafficking

(2009) Marnix Wieffer et al.   CELL

Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia

(2009) Adam J. Funk et al.   NEUROREPORT

Cell and receptor type-specific alterations in markers of GABA neurotransmission in the prefrontal cortex of subjects with schizophrenia

(2009) David A. Lewis et al.   NEUROTOXICITY RESEARCH

The Post-Synaptic Density of Human Postmortem Brain Tissues: An Experimental Study Paradigm for Neuropsychiatric Illnesses

(2009) Chang-Gyu Hahn et al.   PLoS One

2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease

(2009) Jane A. English et al.   PROTEOMICS

The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement

(2008) S R Engel et al.   MOLECULAR PSYCHIATRY

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression

(2008) ÁT Behan et al.   MOLECULAR PSYCHIATRY

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

(2008) John E. Lisman et al.   TRENDS IN NEUROSCIENCES