What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn

Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia

(2012) Anna C. Need et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic and Familial Environmental Influences on the Risk for Drug Abuse

(2012) Kenneth S. Kendler et al.   ARCHIVES OF GENERAL PSYCHIATRY

Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

(2012) Gitta H. Lubke et al.   BIOLOGICAL PSYCHIATRY

Genetics of multiple sclerosis

(2012) Sergio E. Baranzini et al.   CURRENT OPINION IN NEUROLOGY

Evidence from Genetics for a Role of Autophagy and Innate Immunity in IBD Pathogenesis

(2012) Miles Parkes   DIGESTIVE DISEASES

Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height

(2012) Julian C. Lui et al.   HUMAN MOLECULAR GENETICS

The dappled nature of causes of psychiatric illness: replacing the organic–functional/hardware–software dichotomy with empirically based pluralism

(2012) K S Kendler   MOLECULAR PSYCHIATRY

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

(2012) M Ayalew et al.   MOLECULAR PSYCHIATRY

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

(2012) S Hong Lee et al.   NATURE GENETICS

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

From circuits to behavior: a bridge too far?

(2012) Matteo Carandini   NATURE NEUROSCIENCE

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

The Emerging Biology of Autism Spectrum Disorders

(2012) M. W. State et al.   SCIENCE

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia

(2012) Peilin Jia et al.   PLoS Computational Biology

Common genetic variants, acting additively, are a major source of risk for autism

(2012) Lambertus Klei et al.   Molecular Autism

Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

(2012) P H Lee et al.   Translational Psychiatry

The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI

(2012) H C Whalley et al.   Translational Psychiatry

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

(2011) Douglas F. Levinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Recent Advances in the Genetics of Parkinson's Disease

(2011) Ian Martin et al.   Annual Review of Genomics and Human Genetics

A Multivariate Twin Study of the DSM-IV Criteria for Antisocial Personality Disorder

(2011) Kenneth S. Kendler et al.   BIOLOGICAL PSYCHIATRY

Polygenic dissection of the bipolar phenotype

(2011) M. L. Hamshere et al.   BRITISH JOURNAL OF PSYCHIATRY

Levels of explanation in psychiatric and substance use disorders: implications for the development of an etiologically based nosology

(2011) K S Kendler   MOLECULAR PSYCHIATRY

Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence

(2011) K S Kendler et al.   MOLECULAR PSYCHIATRY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Exome sequencing supports a de novo mutational paradigm for schizophrenia

(2011) Bin Xu et al.   NATURE GENETICS

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Toward a Comprehensive Developmental Model for Alcohol Use Disorders in Men

(2011) Kenneth S. Kendler et al.   Twin Research and Human Genetics

Genetic and environmental influences on cannabis use initiation and problematic use: a meta-analysis of twin studies

(2010) Karin J. H. Verweij et al.   ADDICTION

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

(2010) C O'Dushlaine et al.   MOLECULAR PSYCHIATRY

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Developmental Twin Study of Church Attendance and Alcohol and Nicotine Consumption: A Model for Analyzing the Changing Impact of Genes and Environment

(2009) Kenneth S. Kendler et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

(2009)   AMERICAN JOURNAL OF PSYCHIATRY

A genome-wide association study in 574 schizophrenia trios using DNA pooling

(2008) G Kirov et al.   MOLECULAR PSYCHIATRY

Rare chromosomal deletions and duplications increase risk of schizophrenia

(2008) Jennifer L. Stone et al.   NATURE

Applying mouse complex-trait resources to behavioural genetics

(2008) Jonathan Flint et al.   NATURE

Genome-Wide Association Identifies a Common Variant in the Reelin Gene That Increases the Risk of Schizophrenia Only in Women

(2008) Sagiv Shifman et al.   PLoS Genetics

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE