A rare mutation of CACNA1C in a patient with bipolar disorder and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Myelination and oxidative stress alterations in the cerebellum of the G72/G30 transgenic schizophrenia mouse model

(2012) Michaela D. Filiou et al.   JOURNAL OF PSYCHIATRIC RESEARCH

P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

(2012) Daniëlle M. E. van Assema et al.   MOLECULAR IMAGING AND BIOLOGY

Long QT, syndactyly, joint contractures, stroke and novel CACNA1C mutation: Expanding the spectrum of Timothy syndrome

(2011) Jane Gillis et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Outcome measures for traumatic brain injury

(2011) Dhaval Shukla et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Differential expression of genes encoding neuronal ion-channel subunits in major depression, bipolar disorder and schizophrenia: implications for pathophysiology

(2011) Bella Smolin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Timothy Mutation Disrupts the Link between Activation and Inactivation in CaV1.2 Protein

(2011) Katrin Depil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice

(2011) Sanjeewa A. Goonasekera et al.   JOURNAL OF CLINICAL INVESTIGATION

Robust L-type calcium current expression following heterozygous knockout of the Cav1.2 gene in adult mouse heart

(2011) Barbara Rosati et al.   JOURNAL OF PHYSIOLOGY-LONDON

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

(2011) Sergiu P Paşca et al.   NATURE MEDICINE

Mouse model of Timothy syndrome recapitulates triad of autistic traits

(2011) P. L. Bader et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Significant Associations for Variants With Minor Allele Frequency of 5% or Less—An Overview: A HuGE Review

(2010) Orestis A. Panagiotou et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Genetic Variation in CACNA1C Affects Brain Circuitries Related to Mental Illness

(2010) Kristin L. Bigos et al.   ARCHIVES OF GENERAL PSYCHIATRY

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

(2010) Y Liu et al.   MOLECULAR PSYCHIATRY

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons

(2010) B. Schlick et al.   NEUROSCIENCE

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Genetic Polymorphisms of L-Type Calcium Channel α1C and α1D Subunit Genes are Associated With Sensitivity to the Antihypertensive Effects of L-Type Dihydropyridine Calcium-Channel Blockers

(2009) Kei Kamide et al.   CIRCULATION JOURNAL

Gene expression of NMDA receptor subunits in the cerebellum of elderly patients with schizophrenia

(2009) Andrea Schmitt et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

The Role of the Cerebellum in Schizophrenia

(2008) Nancy C. Andreasen et al.   BIOLOGICAL PSYCHIATRY

Proarrhythmic Defects in Timothy Syndrome Require Calmodulin Kinase II

(2008) William H. Thiel et al.   CIRCULATION

The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation

(2008) Viktor Yarotskyy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

(2008) Manuel A R Ferreira et al.   NATURE GENETICS

The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels

(2008) C. F. Barrett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA