Hepatic CYP3A Suppression by High Concentrations of Proteasomal Inhibitors: A Consequence of Endoplasmic Reticulum (ER) Stress Induction, Activation of RNA-Dependent Protein Kinase-Like ER-Bound Eukaryotic Initiation Factor 2 (eIF2 )-Kinase (PERK) and General Control Nonderepressible-2 eIF2 Kinase (GCN2), and Global Translational Shutoff

Published 2009 View Full Article

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Keywords

Journal

MOLECULAR PHARMACOLOGY

Volume 76, Issue 3, Pages 503-515

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Online

2009-06-12

DOI

10.1124/mol.109.056002

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