An LPA Species (18:1 LPA) Plays Key Roles in the Self-Amplification of Spinal LPA Production in the Peripheral Neuropathic Pain Model

Spatiotemporal alteration of phospholipids and prostaglandins in a rat model of spinal cord injury

(2012) Mitsuru Hanada et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lysophospholipids and their receptors in the central nervous system

(2012) Ji Woong Choi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lysophosphatidic acid: Chemical signature of neuropathic pain

(2012) Hiroshi Ueda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lysophosphatidic acid (LPA) and its receptors: Role in airway inflammation and remodeling

(2012) Yutong Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphorylation of ezrin/radixin/moesin (ERM) protein in spinal microglia following peripheral nerve injury and lysophosphatidic acid administration

(2012) Ryosuke Kashimoto et al.   GLIA

Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain

(2012) L. Sun et al.   JOURNAL OF NEUROSCIENCE

Single Application of A2 NTX, a Botulinum Toxin A2 Subunit, Prevents Chronic Pain Over Long Periods in Both Diabetic and Spinal Cord Injury^|^ndash;Induced Neuropathic Pain Models

(2012) Lin Ma et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Lysophosphatidic acid as an initiator of neuropathic pain: biosynthesis and demyelination

(2011) Hiroshi Ueda et al.   Clinical Lipidology

Pre-emptive morphine treatment abolishes nerve injury-induced lysophospholipid synthesis in mass spectrometrical analysis

(2011) Jun Nagai et al.   JOURNAL OF NEUROCHEMISTRY

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

(2011) Hiroshi Nishimasu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

LPA receptor expression in the central nervous system in health and following injury

(2010) Yona Goldshmit et al.   CELL AND TISSUE RESEARCH

Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain

(2010) Weijiao Xie et al.   JOURNAL OF NEUROCHEMISTRY

Microglial activation mediates de novo lysophosphatidic acid production in a model of neuropathic pain

(2010) Lin Ma et al.   JOURNAL OF NEUROCHEMISTRY

Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain

(2010) L. Ma et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Autotaxin and Lysophosphatidic Acid1 receptor-Mediated Demyelination of Dorsal Root Fibers by Sciatic Nerve Injury and Intrathecal Lysophosphatidylcholine

(2010) Jun Nagai et al.   Molecular Pain

A clean-up technology for the simultaneous determination of lysophosphatidic acid and sphingosine-1-phosphate by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a phosphate-capture molecule, Phos-tag

(2010) Jun-ichi Morishige et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Evidence for lysophosphatidic acid 1 receptor signaling in the early phase of neuropathic pain mechanisms in experiments using Ki-16425, a lysophosphatidic acid 1 receptor antagonist

(2009) Lin Ma et al.   JOURNAL OF NEUROCHEMISTRY

Intratrigeminal ganglionic injection of LPA causes neuropathic pain-like behavior and demyelination in rats

(2009) Dong K. Ahn et al.   PAIN

Could a nano-assisted laser desorption/ionization target improve the study of small organic molecules by laser desorption/ionization time-of-flight mass spectrometry?

(2009) Erwann Guénin et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Two pathways for lysophosphatidic acid production

(2008) J AOKI   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Cytotoxic Effect of Bromoenol Lactone, a Calcium-independent Phospholipase A2 Inhibitor, on Rat Cortical Neurons in Culture

(2008) Shiro Kurusu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Lysophosphatidic acid (LPA) and its receptors

(2008) Kyoko Noguchi et al.   CURRENT OPINION IN PHARMACOLOGY

Lysophosphatidic acid-induced membrane ruffling and brain-derived neurotrophic factor gene expression are mediated by ATP release in primary microglia

(2008) Ryousuke Fujita et al.   JOURNAL OF NEUROCHEMISTRY

Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain

(2008) Makoto Inoue et al.   JOURNAL OF NEUROCHEMISTRY

Peripheral Mechanisms of Neuropathic Pain — Involvement of Lysophosphatidic Acid Receptor-Mediated Demyelination

(2008) Hiroshi Ueda   Molecular Pain

Involvement of LPA1 Receptor Signaling in the Reorganization of Spinal Input through Abeta-Fibers in Mice with Partial Sciatic Nerve Injury

(2008) Weijiao Xie et al.   Molecular Pain

G protein–coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth

(2008) Sandra M Pasternack et al.   NATURE GENETICS

Profiling of BoNT/C3-reversible gene expression induced by lysophosphatidic acid: ephrinB1 gene up-regulation underlying neuropathic hyperalgesia and allodynia

(2008) Hitoshi Uchida et al.   NEUROCHEMISTRY INTERNATIONAL