Article
Biochemistry & Molecular Biology
Helena Salgado, Ana T. P. C. Gomes, Ana S. Duarte, Jose M. F. Ferreira, Carlos Fernandes, Maria Helena Figueiral, Pedro Mesquita
Summary: This study tested the antimicrobial activity and surface roughness of a graphene-enhanced dental resin against Candida albicans and Streptococcus mutans. The increase in graphene concentration resulted in increased surface roughness. Graphene was effective in inhibiting the growth and adhesion of C. albicans and S. mutans.
Review
Polymer Science
Yousif A. A. Al-Dulaijan, Abdulrahman A. A. Balhaddad
Summary: DBR materials used in dentistry for constructing dentures and prostheses pose a high risk of denture stomatitis, causing inflammation of soft oral tissues. Fungal attachment, mainly by Candida albicans, to DBRs is a major cause of the disease. Attempts have been made to incorporate antimicrobial compounds and particles into DBRs to prevent microbial attachment. This review explores advanced approaches to designing bioactive and antimicrobial DBR materials, emphasizing the importance of mechanical and physical sustainability.
Article
Polymer Science
Nichakorn Songsang, Chuchai Anunmana, Matsayapan Pudla, Trinuch Eiampongpaiboon
Summary: Incorporating Litsea cubeba essential oil into soft lining materials inhibited the growth of Candida albicans and Streptococcus mutans without affecting cytotoxicity and surface hardness. The higher the concentration of LCEO, the greater the inhibitory effect on oral pathogens without compromising the integrity of the materials.
Article
Biotechnology & Applied Microbiology
Thayse Yumi Hosida, Juliano Pelim Pessan, Thamires Priscila Cavazana, Caio Sampaio, Douglas Roberto Monteiro, Alberto Carlos Botazzo Delbem
Summary: This study evaluated the effect of sodium hexametaphosphate (HMP) alone or in combination with fluoride (F) on dual-species biofilms of Streptococcus mutans and Candida albicans. The results showed that the combination of HMP and F significantly reduced the metabolic activity and biomass of biofilms, but had no significant effect on the CFUs of C. albicans under certain conditions.
Article
Engineering, Biomedical
Chiaki Tsutsumi-Arai, Yuki Arai, Chika Terada-Ito, Takahiro Imamura, Seiko Tatehara, Shinji Ide, Noriyuki Wakabayashi, Kazuhito Satomura
Summary: The study demonstrated that 405-nm blue LED light irradiation effectively disinfects Candida albicans hyphae and Streptococcus mutans dual-species biofilms, possibly by reacting with intracellular porphyrins to generate ROS in each microorganism.
LASERS IN MEDICAL SCIENCE
(2022)
Article
Infectious Diseases
Thayse Yumi Hosida, Juliano Pelim Pessan, Thamires Priscila Cavazana, Caio Sampaio, Leonardo Antonio de Morais, Douglas Roberto Monteiro, Alberto Carlos Botazzo Delbem
Summary: This study evaluated the effects of sodium hexametaphosphate (HMP) and/or fluoride (F) on the inorganic components and pH of Streptococcus mutans and Candida albicans dual-species biofilms. It was found that HMP, combined with F, increased F levels and decreased P levels in the biofilm fluid, while promoting a higher pH.
Article
Dentistry, Oral Surgery & Medicine
Thamires Priscila Cavazana, Thayse Yumi Hosida, Caio Sampaio, Leonardo Antonio de Morais, Douglas Roberto Monteiro, Juliano Pelim Pessan, Alberto Carlos Botazzo Delbem
Summary: The study evaluated the influence of CaGP and F on pH and concentrations of F, Ca, and P in dual-species biofilms, showing that combined treatment led to higher pH and concentrations in the biofilm biomass, while CaGP alone increased Ca and P concentrations in the biofilm fluid.
JOURNAL OF DENTISTRY
(2021)
Article
Biotechnology & Applied Microbiology
Caio Sampaio, Alberto Carlos Botazzo Delbem, Thayse Yumi Hosida, Leonardo Antonio de Morais, Ana Vitoria Pereira Fernandes, Francisco Nunes Souza Neto, Emerson Rodrigues de Camargo, Douglas Roberto Monteiro, Juliano Pelim Pessan
Summary: This study evaluated the effects of micrometric or nano-sized sodium hexametaphosphate, combined or not with fluoride, on dual-species biofilms of Streptococcus mutans and Candida albicans. The results showed that the nano-sized sodium hexametaphosphate and fluoride had stronger antibacterial effects on the biofilms.
Article
Microbiology
Yuan Liu, Scott G. G. Daniel, Hye-Eun Kim, Hyun Koo, Jonathan Korostoff, Flavia Teles, Kyle Bittinger, Geelsu Hwang
Summary: In this study, a novel ex vivo saliva-derived microcosm biofilm model was used to investigate the effects of S. mutans and C. albicans as well as different sugars on the composition and function of the oral microbiome. The presence of S. mutans and C. albicans, either alone or in combination, and the addition of different sugars led to unique changes in the biofilm. The combination of S. mutans and C. albicans appeared to drive the development and severity of a dysbiotic/cariogenic oral microbiome.
Article
Engineering, Biomedical
Chiaki Tsutsumi-Arai, Yuki Arai, Chika Terada-Ito, Takahiro Imamura, Seiko Tatehara, Shinji Ide, Jumpei Shirakawa, Noriyuki Wakabayashi, Kazuhito Satomura
Summary: This study investigated the inhibitory effect of irradiation with 405-nm blue LED light on the growth of Candida albicans and Streptococcus mutans biofilms on denture base resin. The results showed that irradiation effectively inhibited the growth of the dual-species biofilms and caused changes in gene expression related to adhesion and biofilm formation.
LASERS IN MEDICAL SCIENCE
(2022)
Article
Engineering, Biomedical
Diego Dantas Lopes dos Santos, Joao Felipe Besegato, Priscila Borges Gobbo de Melo, Joao Augusto Oshiro Junior, Marlus Chorilli, Dongmei Deng, Vanderlei Salvador Bagnato, Alessandra Nara de Souza Rastelli
Summary: The study demonstrates that curcumin-encapsulated Pluronic(R) F-127 in antimicrobial photodynamic therapy can effectively reduce the viability of dual-species biofilm of Streptococcus mutans and Candida albicans, suggesting a potential strategy for biofilm control in oral health.
LASERS IN MEDICAL SCIENCE
(2022)
Article
Polymer Science
Salwa Omar Bajunaid, Bashayer H. Baras, Michael D. Weir, Hockin H. K. Xu
Summary: This study investigated the incorporation of MPC and DMAHDM into a denture base material for the treatment of denture stomatitis. The results demonstrated that the dual incorporation of MPC and DMAHDM significantly reduced the adherence of C. albicans and could potentially reduce the prevalence of denture stomatitis. However, the addition of these bioactive agents reduced the flexural strength of the material and had some impact on surface roughness.
Article
Dentistry, Oral Surgery & Medicine
Loubna Shamseddine, Jose Johann Chidiac
Summary: This research aimed to evaluate the antibacterial and antifungal properties of Origanum Syriacum essential oils, quantify their bactericidal and fungicidal minimal concentration against specific microorganisms, and explore the impact of different soils on essential oil composition. The study found that all tested essential oils were effective against microorganisms, with oils from Annaya and Bhanin soils exhibiting superior antimicrobial activity. The most abundant and efficient component in the oils was carvacrol, suggesting potential for clinical trials in treating denture stomatitis.
Article
Chemistry, Multidisciplinary
Viviane de Oliveira Zequini Amarante, Alberto Carlos Botazzo Delbem, Caio Sampaio, Leonardo Antonio de Morais, Emerson Rodrigues de Camargo, Douglas Roberto Monteiro, Juliano Pelim Pessan, Thayse Yumi Hosida
Summary: This study evaluated the effects of sodium trimetaphosphate nanoparticles (TMPn) on dual-species biofilms of Streptococcus mutans and Candida albicans. The results showed that 3% TMPn/F significantly reduced carbohydrate content and increased pH in the biofilms after sucrose exposure. In addition, it increased phosphorus (P) and fluoride (F) levels in the biofilm fluid before sucrose exposure.
Article
Biotechnology & Applied Microbiology
Joel Oliveira Barreto, Francisca Bruna Stefany Aires do Nascimento, Said Goncalves da Cruz Fonseca, Leticia Serpa Sampaio, Cecilia Rocha da Silva, Joao Batista de Andrade Neto, Helio Vitoriano Nobre JUnior, Romulo Rocha Regis
Summary: The experimental solution containing Lippia sidoides essential oil showed antimicrobial activity against different pathogens, reduced the metabolic activity of C. albicans biofilm significantly, and caused cell wall damage at low concentrations, making it a potential alternative for the prevention and treatment of denture-induced infections.
Review
Chemistry, Analytical
Chunsheng Wu, Peter B. Lillehoj, Ping Wang
Article
Biochemical Research Methods
Xiyuan Liu, Peter B. Lillehoj
Article
Biochemical Research Methods
Tung-Yi Lin, Truong Do, Patrick Kwon, Peter B. Lillehoj
Article
Chemistry, Multidisciplinary
Tung-Yi Lin, Trey T. Pfeiffer, Peter B. Lillehoj
Article
Engineering, Biomedical
Xiyuan Liu, Tung-Yi Lin, Peter B. Lillehoj
ANNALS OF BIOMEDICAL ENGINEERING
(2014)
Article
Biochemical Research Methods
Peter B. Lillehoj, Ming-Chun Huang, Newton Truong, Chih-Ming Ho
Review
Chemistry, Analytical
Nirmita Dutta, Peter B. Lillehoj, Pedro Estrela, Gorachand Dutta
Summary: Cytokines play crucial roles in immune regulation, with their aberrant expression possibly linked to diseases. Cytokine profiling can aid in diagnosing and monitoring disease progression, as well as evaluating the efficacy of immunotherapy.
Proceedings Paper
Engineering, Electrical & Electronic
Tung-Yi Lin, Sina Parsenjad, Linlin Tu, Trey T. Pfeiffer, Andrew J. Mason, Guoliang Xing, Peter B. Lillehoj
2017 IEEE 12TH INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS (NEMS)
(2017)
Proceedings Paper
Engineering, Electrical & Electronic
Xue Jiang, Peter B. Lillehoj
2017 IEEE 12TH INTERNATIONAL CONFERENCE ON NANO/MICRO ENGINEERED AND MOLECULAR SYSTEMS (NEMS)
(2017)
Article
Biophysics
Xiyuan Liu, Peter B. Lillehoj
BIOSENSORS & BIOELECTRONICS
(2017)
Article
Chemistry, Analytical
Gorachand Dutta, Peter B. Lillehoj
Article
Biophysics
Gorachand Dutta, Sureshbabu Nagarajan, Lisa J. Lapidus, Peter B. Lillehoj
BIOSENSORS & BIOELECTRONICS
(2017)
Proceedings Paper
Energy & Fuels
X. Liu, P. B. Lillehoj
15TH INTERNATIONAL CONFERENCE ON MICRO AND NANOTECHNOLOGY FOR POWER GENERATION AND ENERGY CONVERSION APPLICATIONS (POWERMEMS 2015)
(2015)
Article
Biochemical Research Methods
Xiyuan Liu, Peter B. Lillehoj
Article
Biochemical Research Methods
Peter B. Lillehoj, Christopher W. Kaplan, Jian He, Wenyuan Shi, Chih-Ming Ho