ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin-1-dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease

(2016) Dean Gilham et al.   ATHEROSCLEROSIS

miR-183 functions as an oncogene by targeting ABCA1 in colon cancer

(2016) DA-PENG BI et al.   ONCOLOGY REPORTS

High-density Lipoproteins and Apolipoprotein A-I: Potential New Players in the Prevention and Treatment of Lung Disease

(2016) Elizabeth M. Gordon et al.   Frontiers in Pharmacology

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients

(2015) Teodoro Vargas et al.   Oncotarget

A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy

(2015) Ruth Sánchez-Martínez et al.   Oncotarget

Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients

(2015) Jian-Liang Chou et al.   Clinical Epigenetics

Apolipoprotein A-I expression suppresses COX-2 expression by reducing reactive oxygen species in hepatocytes

(2014) Jing Mao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer

(2014) Jian Shi et al.   CANCER CELL

ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer

(2014) Ellen L. Hedditch et al.   JNCI-Journal of the National Cancer Institute

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

(2014) L Jiang et al.   ONCOGENE

PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

(2013) Nam-Hu Her et al.   CELL CYCLE

Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma

(2013) Z. Cheng et al.   CLINICAL CANCER RESEARCH

The Cardioprotective Protein Apolipoprotein A1 Promotes Potent Anti-tumorigenic Effects

(2013) Maryam Zamanian-Daryoush et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition

(2013) Alexandre Puissant et al.   Cancer Discovery

Dysregulation of Cholesterol Homeostasis in Human Prostate Cancer through Loss of ABCA1

(2012) B. H. Lee et al.   CANCER RESEARCH

Caveolin-1-Enhanced Motility and Focal Adhesion Turnover Require Tyrosine-14 but Not Accumulation to the Rear in Metastatic Cancer Cells

(2012) Hery Urra et al.   PLoS One

Development of Multiplexed Bead-Based Immunoassays for the Detection of Early Stage Ovarian Cancer Using a Combination of Serum Biomarkers

(2012) Yong-Wan Kim et al.   PLoS One

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Anticancer Activity of the Cholesterol Exporter ABCA1 Gene

(2012) Bradley Smith et al.   Cell Reports

Proteomic biomarkers apolipoprotein A1, truncated transthyretin and connective tissue activating protein III enhance the sensitivity of CA125 for detecting early stage epithelial ovarian cancer

(2011) Charlotte H. Clarke et al.   GYNECOLOGIC ONCOLOGY

A novel model of cholesterol efflux from lipid-loaded cells

(2010) Di-xian Luo et al.   ACTA PHARMACOLOGICA SINICA

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Caveolin-1 in tumor progression: the good, the bad and the ugly

(2008) Jacky G. Goetz et al.   CANCER AND METASTASIS REVIEWS