Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth

Cancer-associated missense mutations of caspase-8 activate nuclear factor-κB signaling

(2013) Mizuo Ando et al.   CANCER SCIENCE

Liberation of functional p53 by proteasome inhibition in human papilloma virus-positive head and neck squamous cell carcinoma cells promotes apoptosis and cell cycle arrest

(2013) Changyou Li et al.   CELL CYCLE

Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers

(2013) C. R. Pickering et al.   Cancer Discovery

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

(2012) Laura S. Dickens et al.   MOLECULAR CELL

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model

(2012) Kolja Schleich et al.   MOLECULAR CELL

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Autophagic degradation of active caspase-8

(2010) Wen Hou et al.   Autophagy

Emerging drugs to treat squamous cell carcinomas of the head and neck

(2010) Christopher Fung et al.   EXPERT OPINION ON EMERGING DRUGS

From procaspase-8 to caspase-8: Revisiting structural functions of caspase-8

(2010) Yang Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

(2009) James A Bonner et al.   LANCET ONCOLOGY

Rab5 Mediates Caspase-8–promoted Cell Motility and Metastasis

(2009) Vicente A. Torres et al.   MOLECULAR BIOLOGY OF THE CELL

Caspase-8 in cancer biology and therapy

(2008) Simone Fulda   CANCER LETTERS

Caspase-8: Fly or Die

(2008) S. M. Frisch   CANCER RESEARCH

Identification of a Critical Tyrosine Residue in Caspase 8 That Promotes Cell Migration

(2008) Simone Barbero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY