Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib

KRAS and BRAF Mutations Predict Primary Resistance to Imatinib in Gastrointestinal Stromal Tumors

(2012) C. Miranda et al.   CLINICAL CANCER RESEARCH

Mutational spectrum and therapy response of metastasized GIST in Central Switzerland – A population-based study

(2011) Matthias Rössle et al.   EUROPEAN JOURNAL OF CANCER

Targeted therapy in GIST: in silico modeling for prediction of resistance

(2011) Marco A. Pierotti et al.   Nature Reviews Clinical Oncology

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: An imaging, biochemical and molecular modeling study

(2010) Palma Dileo et al.   INTERNATIONAL JOURNAL OF CANCER

Imatinib treatment for gastrointestinal stromal tumour (GIST)

(2009) Lisandro F. Lopes et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

T670X KIT Mutations in Gastrointestinal Stromal Tumors: Making Sense of Missense

(2009) T. Negri et al.   JNCI-Journal of the National Cancer Institute

Activate and resist: L576P-KIT in GIST

(2009) E. Conca et al.   MOLECULAR CANCER THERAPEUTICS

Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates

(2009) S. E. Woodman et al.   MOLECULAR CANCER THERAPEUTICS

Targeted Therapies: The Rare Cancer Paradigm

(2009) Marco A. Pierotti et al.   Molecular Oncology

Clinical significance of oncogenicKITandPDGFRAmutations in gastrointestinal stromal tumours

(2008) J Lasota et al.   HISTOPATHOLOGY

Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing KIT

(2008) Charles D. Blanke et al.   JOURNAL OF CLINICAL ONCOLOGY

Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor

(2008) Michael C. Heinrich et al.   JOURNAL OF CLINICAL ONCOLOGY

Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors

(2008) John C. McAuliffe et al.   Molecular Oncology