Plumbagin, a medicinal plant (lumbago zeylanica )-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model

Activation of Urokinase Plasminogen Activator and Its Receptor Axis Is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model

(2015) Jian Zhang et al.   NEOPLASIA

Targeted Antivascular Therapy with the Apolipoprotein(a) Kringle V, rhLK8, Inhibits the Growth and Metastasis of Human Prostate Cancer in an Orthotopic Nude Mouse Model

(2015) Ho-Jeong Lee et al.   NEOPLASIA

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKC , Stat3 and neuroendocrine markers

(2012) B. B. Hafeez et al.   CARCINOGENESIS

Plumbagin Inhibits Breast Tumor Bone Metastasis and Osteolysis by Modulating the Tumor-Bone Microenvironment

(2012) Z. Li et al.   CURRENT MOLECULAR MEDICINE

Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH

(2012) Audrey Courboulin et al.   EUROPEAN RESPIRATORY JOURNAL

Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways

(2012) Bilal Bin Hafeez et al.   INTERNATIONAL JOURNAL OF CANCER

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cellsin vivo

(2012) Sutapa Sinha et al.   INTERNATIONAL JOURNAL OF CANCER

Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma

(2011) B. B. Hafeez et al.   CANCER RESEARCH

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from Plumbago zeylanica, inhibits ultraviolet radiation-induced development of squamous cell carcinomas

(2011) J. M. Sand et al.   CARCINOGENESIS

Transgenic overexpression of PKCε in the mouse prostate induces preneoplastic lesions

(2011) Fernando Benavides et al.   CELL CYCLE

Overexpression of MMP-9 Contributes to Invasiveness of Prostate Cancer Cell Line LNCaP

(2011) Ravikumar Aalinkeel et al.   IMMUNOLOGICAL INVESTIGATIONS

Prognostic impact of nm23-H1 and PCNA expression in pathologic stage I non-small cell lung cancer

(2011) Chengying Liu et al.   JOURNAL OF SURGICAL ONCOLOGY

Targeting Tyrosine Phosphorylation of PCNA Inhibits Prostate Cancer Growth

(2011) H. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-Induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling

(2011) B. Sung et al.   MOLECULAR CANCER THERAPEUTICS

Matrix Metalloproteinases and Angiogenic Factors

(2010) Silvan Boxler et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer

(2010) Jonathan A. Coulter et al.   JOURNAL OF GENE MEDICINE

Perspectives on medicinal properties of plumbagin and its analogs

(2010) Subhash Padhye et al.   MEDICINAL RESEARCH REVIEWS

Protein kinase Cɛ mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2 and ERK1/2)

(2010) M H Aziz et al.   ONCOGENE

Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin

(2009) Kodihalli C. Ravindra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

(2009) Tae Gen Son et al.   JOURNAL OF NEUROCHEMISTRY

Plumbagin, a Medicinal Plant–Derived Naphthoquinone, Is a Novel Inhibitor of the Growth and Invasion of Hormone-Refractory Prostate Cancer

(2008) Moammir H. Aziz et al.   CANCER RESEARCH

Plumbagin-induced Apoptosis in Human Prostate Cancer Cells is Associated with Modulation of Cellular Redox Status and Generation of Reactive Oxygen Species

(2008) Anna A. Powolny et al.   PHARMACEUTICAL RESEARCH

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

(2007) Clay C.C. Wang et al.   CANCER LETTERS