High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the γ-secretase inhibitor, RO4929097

ADAM17 Regulates Epidermal Growth Factor Receptor Expression through the Activation of Notch1 in Non-Small Cell Lung Cancer

(2010) A. Baumgart et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor--A Positive and Negative Regulator of Tumor Growth

(2010) L. M. Vecchiarelli-Federico et al.   CANCER RESEARCH

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

Preclinical Profile of a Potent  -Secretase Inhibitor Targeting Notch Signaling with In vivo Efficacy and Pharmacodynamic Properties

(2009) L. Luistro et al.   CANCER RESEARCH

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications

(2009) Ji-Liang Li   Frontiers in Bioscience-Landmark

A Notch updated

(2009) An-Chi Tien et al.   JOURNAL OF CELL BIOLOGY

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way

(2009) Peter Carmeliet et al.   Nature Reviews Clinical Oncology

Deciphering the genetic landscape of cancer – from genes to pathways

(2009) Neal G. Copeland et al.   TRENDS IN GENETICS

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Chemotherapeutic drugs and human tumor cells cytokine network

(2008) Vera Levina et al.   INTERNATIONAL JOURNAL OF CANCER

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NFκB through the CBM (Carma3/Bcl10/Malt1) Complex

(2008) Daniel Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The many facets of Notch ligands

(2008) B D'Souza et al.   ONCOGENE

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE