Triple-negative breast cancer: Present challenges and new perspectives

Triple negative breast cancer - current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment

(2012) Katerina Bouchalova et al.   BIOMEDICAL PAPERS-OLOMOUC

Triple-negative breast cancer: Molecular features, pathogenesis, treatment and current lines of research

(2010) Ana Bosch et al.   CANCER TREATMENT REVIEWS

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

(2009) B. Corkery et al.   ANNALS OF ONCOLOGY

Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2009

(2009) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Combining tissue transcriptomics and urine metabolomics for breast cancer biomarker identification

(2009) Hojung Nam et al.   BIOINFORMATICS

Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis

(2009) Ronglai Shen et al.   BIOINFORMATICS

Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation

(2009) Roberta Alfieri et al.   BMC BIOINFORMATICS

TIde: a software for the systematic scanning of drug targets in kinetic network models

(2009) Marvin Schulz et al.   BMC BIOINFORMATICS

Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection

(2009) Carsten Henneges et al.   BMC CANCER

T1N0 Triple Negative Breast Cancer: Risk of Recurrence and Adjuvant Chemotherapy

(2009) Henry G. Kaplan et al.   Breast Journal

Molecular classification of solid tumours: towards pathway-driven therapeutics

(2009) C Swanton et al.   BRITISH JOURNAL OF CANCER

The epidemiology of triple-negative breast cancer, including race

(2009) Katrina F. Trivers et al.   CANCER CAUSES & CONTROL

Cell biology of the movement of breast cancer cells: Intracellular signalling and the actin cytoskeleton

(2009) Ping Jiang et al.   CANCER LETTERS

Survival Outcomes for Patients with Metastatic Triple-Negative Breast Cancer: Implications for Clinical Practice and Trial Design

(2009) Farrah Kassam et al.   Clinical Breast Cancer

Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes

(2009) E. A. Rakha et al.   CLINICAL CANCER RESEARCH

3LBA SOLTI-0701: A double-blind, randomized phase 2b study evaluating the efficacy and safety of sorafenib (SOR) compared to placebo (PL) when administered in combination with capecitabine (CAP) in patients (pts) with locally advanced (adv) or metastatic (met) breast cancer (BC)

(2009) J. Baselga et al.   EJC SUPPLEMENTS

Triple negative breast cancers: Clinical and prognostic implications

(2009) S.J. Dawson et al.   EUROPEAN JOURNAL OF CANCER

A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts

(2009) Nils Blüthgen et al.   FEBS Journal

What’s positive about ‘triple-negative’ breast cancer?

(2009) Sara A Hurvitz et al.   Future Oncology

Inferring tumor progression from genomic heterogeneity

(2009) N. Navin et al.   GENOME RESEARCH

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrating Biological Knowledge with Gene Expression Profiles for Survival Prediction of Cancer

(2009) Xi Chen et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Multivariate Modeling and Prediction of Breast Cancer Prognostic Factors Using MR Metabolomics

(2009) Guro F. Giskeødegård et al.   JOURNAL OF PROTEOME RESEARCH

A quantitative model of the effect of unreplicated DNA on cell cycle progression in frog egg extracts

(2009) Jason Zwolak et al.   JOURNAL OF THEORETICAL BIOLOGY

HIF-1α Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms

(2009) Alvaro Marin-Hernandez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

(2009) Nikolay Borisov et al.   Molecular Systems Biology

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

(2009) William W Chen et al.   Molecular Systems Biology

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response

(2009) Sanjay Chandriani et al.   PLoS One

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis?

(2009) Wolfgang Bogner et al.   RADIOLOGY

Triple-Negative Breast Cancer: Correlation between MR Imaging and Pathologic Findings

(2009) Takayoshi Uematsu et al.   RADIOLOGY

MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells

(2009) D. Iliopoulos et al.   Science Signaling

Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor-PI3K Axis

(2009) B. Schoeberl et al.   Science Signaling

The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data

(2009) Regina Samaga et al.   PLoS Computational Biology

Platinum-based chemotherapy in triple-negative breast cancer

(2008) B. Sirohi et al.   ANNALS OF ONCOLOGY

The prognostic importance of triple negative breast carcinoma

(2008) Hakan Mersin et al.   BREAST

Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis

(2008) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

Clinical proteomics in breast cancer: a review

(2008) Marie-Christine W. Gast et al.   BREAST CANCER RESEARCH AND TREATMENT

Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patients

(2008) T. Byrski et al.   BREAST CANCER RESEARCH AND TREATMENT

Invasive ductal carcinoma of the breast with the “triple-negative” phenotype: prognostic implications of EGFR immunoreactivity

(2008) Giuseppe Viale et al.   BREAST CANCER RESEARCH AND TREATMENT

Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA

(2008) Mary Jo Lund et al.   BREAST CANCER RESEARCH AND TREATMENT

Therapeutic Strategies for Triple-Negative Breast Cancer

(2008) Antoinette R. Tan et al.   CANCER JOURNAL

Subtypes of Breast Cancer Show Preferential Site of Relapse

(2008) M. Smid et al.   CANCER RESEARCH

An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes

(2008) L. Melchor et al.   CARCINOGENESIS

Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers

(2008) Han Min Woo et al.   CLINICA CHIMICA ACTA

Emerging Biomarkers and New Understanding of Traditional Markers in Personalized Therapy for Breast Cancer

(2008) M. Dowsett et al.   CLINICAL CANCER RESEARCH

Basal-Like Breast Cancer Defined by Five Biomarkers Has Superior Prognostic Value than Triple-Negative Phenotype

(2008) M. C.U. Cheang et al.   CLINICAL CANCER RESEARCH

Triple-Negative Breast Cancer: Risk Factors to Potential Targets

(2008) B. P. Schneider et al.   CLINICAL CANCER RESEARCH

Triple-negative breast cancer

(2008) Gert Stockmans et al.   CURRENT OPINION IN ONCOLOGY

PET Imaging of Steroid Receptor Expression in Breast and Prostate Cancer

(2008) G. Hospers et al.   CURRENT PHARMACEUTICAL DESIGN

What is triple-negative breast cancer?

(2008) William J. Irvin et al.   EUROPEAN JOURNAL OF CANCER

Development of therapeutic approaches to ‘triple negative’ phenotype breast cancer

(2008) Kai-Keen Shiu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer

(2008) Chaitanya R. Acharya   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Basal-Like Breast Cancer: A Critical Review

(2008) Emad A. Rakha et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Study of Sunitinib Malate, an Oral Multitargeted Tyrosine Kinase Inhibitor, in Patients With Metastatic Breast Cancer Previously Treated With an Anthracycline and a Taxane

(2008) Harold J. Burstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Genomics Study of Ixabepilone as Neoadjuvant Treatment for Breast Cancer

(2008) José Baselga et al.   JOURNAL OF CLINICAL ONCOLOGY

Refinement of breast cancer classification by molecular characterization of histological special types

(2008) B Weigelt et al.   JOURNAL OF PATHOLOGY

Multiproject–multicenter evaluation of automatic brain tumor classification by magnetic resonance spectroscopy

(2008) Juan M. García-Gómez et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Report on EU-USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008)

(2008) Ruedi Aebersold et al.   Molecular Oncology

A Computational Model for Understanding Stem Cell, Trophectoderm and Endoderm Lineage Determination

(2008) Vijay Chickarmane et al.   PLoS One

Molecular insights into human daily behavior

(2008) S. A. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

(2008) B. Schmierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topoisomerase levels determine chemotherapy responsein vitroandin vivo

(2008) Darren J. Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution magic angle spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer

(2008) Beathe Sitter et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Estrogen Receptor–Negative Invasive Breast Cancer: Imaging Features of Tumors with and without Human Epidermal Growth Factor Receptor Type 2 Overexpression

(2008) Yingbing Wang et al.   RADIOLOGY

Comparison of triple-negative and estrogen receptor-positive/progesterone receptor-positive/HER2-negative breast carcinoma using quantitative fluorine-18 fluorodeoxyglucose/positron emission tomography imaging parameters

(2007) Sandip Basu et al.   CANCER