Journal
MOLECULAR NUTRITION & FOOD RESEARCH
Volume 58, Issue 11, Pages 2235-2238Publisher
WILEY
DOI: 10.1002/mnfr.201400013
Keywords
Glucose tolerance; Polyphenols; Potato; Sex differences
Categories
Funding
- Natural Sciences and Engineering Council of Canada
- Canadian Institutes of Health Research
- Canada Foundation for Innovation
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Both sexes of mice were fed a high fat diet (HFD) for 10 weeks without and with polyphenolic-rich potato extracts (PRPE) of cultivars Onaway and Russet Burbank. PRPE attenuated weight gain in male and female mice by as much as 63.2%, which was associated mostly with a reduction in adiposity. Mice receiving PRPE showed enhanced capacity for blood glucose clearance. Sex differences regarding the impact of HFD and PRPE on plasma levels of insulin, ghrelin, leptin, gastric inhibitory peptide, and resistin were noted. PRPE may serve as part of a preventative dietary strategy against the development of obesity and type 2 diabetes.
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