Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice

Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR

(2013) Jordan Gallinetti et al.   BIOCHEMICAL JOURNAL

Leucine and mTORC1: a complex relationship

(2012) Kayleigh M. Dodd et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Age-related changes in serum amino acids concentrations in healthy individuals

(2012) Takanori Kouchiwa et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

(2012) Alejo Efeyan et al.   NATURE

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

(2012) Barbara Chaneton et al.   NATURE

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

(2012) Oliver D. K. Maddocks et al.   NATURE

In Vivo Diagnostic Imaging Using Micro-CT: Sequential and Comparative Evaluation of Rodent Models for Hepatic/Brain Ischemia and Stroke

(2012) Naoto Hayasaka et al.   PLoS One

Non-Invasive Quantification of White and Brown Adipose Tissues and Liver Fat Content by Computed Tomography in Mice

(2012) Marko Lubura et al.   PLoS One

Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice

(2012) W. Peng et al.   Science Translational Medicine

The Anterior Piriform Cortex Is Sufficient for Detecting Depletion of an Indispensable Amino Acid, Showing Independent Cortical Sensory Function

(2011) J. B. Rudell et al.   JOURNAL OF NEUROSCIENCE

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury

(2010) Isao Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

(2009) Harinder S. Hundal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia

(2008) Noriyuki Akahoshi et al.   HUMAN MOLECULAR GENETICS

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE