The dietary terpene lupeol targets colorectal cancer cells with constitutively active Wnt/β-catenin signaling

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Common Role for Various Human Truncated Adenomatous Polyposis Coli Isoforms in the Control of Beta-Catenin Activity and Cell Proliferation

(2012) Shree Harsha Vijaya Chandra et al.   PLoS One

Modulation of Wnt/ -catenin signaling pathway by bioactive food components

(2011) R. S. Tarapore et al.   CARCINOGENESIS

New perspectives on APC control of cell fate and proliferation in colorectal cancer

(2011) Reid A. Phelps et al.   CELL CYCLE

Specific targeting of Wnt/ -catenin signaling in human melanoma cells by a dietary triterpene lupeol

(2010) R. S. Tarapore et al.   CARCINOGENESIS

Lupeol triterpene, a novel diet-based microtubule targeting agent: Disrupts survivin/cFLIP activation in prostate cancer cells

(2009) Mohammad Saleem et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lupeol, a Dietary Triterpene, Inhibited Growth, and Induced Apoptosis Through Down-Regulation of DR3 in SMMC7721 Cells

(2009) Lin Zhang et al.   CANCER INVESTIGATION

Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene

(2009) Mohammad Saleem   CANCER LETTERS

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Melanoma cell differentiation induced by lupeol separates into two stages: morphological and functional changes

(2009) Kikumi Ogiwara et al.   Journal of Natural Medicines

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Lupeol Inhibits Growth of Highly Aggressive Human Metastatic Melanoma Cells In vitro and In vivo by Inducing Apoptosis

(2008) M. Saleem et al.   CLINICAL CANCER RESEARCH

The triterpenoid lupeol attenuates allergic airway inflammation in a murine model

(2008) J.F. Vasconcelos et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a

(2008) Zhongyan Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Overexpression of mRNA-binding protein CRD-BP in malignant melanomas

(2008) I Elcheva et al.   ONCOGENE

Cancer Chemoprevention Through Dietary Antioxidants: Progress and Promise

(2007) Naghma Khan et al.   ANTIOXIDANTS & REDOX SIGNALING