Review
Chemistry, Physical
Zhiqiang Zou, Lingmei Dai, Dehua Liu, Wei Du
Summary: Vitamin E is easily oxidized, limiting its applications, but its ester derivatives show improved stability and antioxidant capacity with new biological functions. Enzymatic synthesis of these derivatives is gaining attention for its environmental friendliness, high catalytic efficiency, and selectivity. Recent studies focus on lipase-mediated preparation of vitamin E ester derivatives, highlighting factors influencing the enzymatic acylation process and discussing the potential of lipase-catalyzed synthesis.
Article
Biochemistry & Molecular Biology
Angelo Azzi
Summary: Vitamin E, specifically alpha-tocopherol, was identified in the 1930s, followed by the isolation of beta-tocopherol, delta-tocopherol, and tocotrienol in subsequent years. In 1981, inherited vitamin E deficiency causing a neuromyopathy, known as AVED, was localized to chromosome 8q due to a mutation in the aTTP gene.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Editorial Material
Multidisciplinary Sciences
Katharine Sanderson, Miryam Naddaf
Summary: UK researchers have been excluded from the scheme for two years due to disagreements over Brexit.
Article
Multidisciplinary Sciences
Loren Kocillari, Mark E. Olson, Samir Suweis, Rodrigo P. Rocha, Alberto Lovison, Franco Cardin, Todd E. Dawson, Alberto Echeverria, Alex Fajardo, Silvia Lechthaler, Cecilia Martinez-Perez, Carmen Regina Marcati, Kuo-Fang Chung, Julieta A. Rosell, Ali Segovia-Rivas, Cameron B. Williams, Emilio Petrone-Mendoza, Andrea Rinaldo, Tommaso Anfodillo, Jayanth R. Banavar, Amos Maritan
Summary: Plants play a crucial role in shaping global water and carbon cycles through the transportation of water via xylem conduits. The Widened Pipe Model (WPM) proposes that xylem conduits should have a specific profile along plant stems, balancing between hydraulic efficiency and carbon cost. The data analysis supports the WPM predictions, highlighting the influence of natural selection on plant hydraulic evolution.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Pharmacology & Pharmacy
Bingqing Zhu, Qi Zhang, Liye Lu, Junjie Bao, Xiaoyi Rong, Jian-Rong Wang, Xuefeng Mei
Summary: This study introduces a more effective method to stabilize and solidify d-alpha-tocopherol oil through cocrystallization, increasing its stability and transforming it into solid form.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Applied
Shigesaburo Ogawa, Katsuya Iuchi, Taro Tsubomura, Kiichiro Totani, Setsuko Hara
Summary: This study reveals that vitamin E nanoemulsion can be easily formed in water-based media through existing protocols. The nanosized vitamin E particles show excellent antioxidant performance and cell protection effect.
JOURNAL OF OLEO SCIENCE
(2022)
Review
Food Science & Technology
Xin-Yu Li, Lei Meng, Liang Shen, Hong-Fang Ji
Summary: Vitamin C (VC), vitamin E (VE), and beta-carotene (beta C) are dietary antioxidants that can enhance the body's antioxidant capacity. Their effects on the gut microbiota were reviewed in this article, with 19 studies included. VC, VE, and beta C can modulate the composition and activity of the gut microbiota, improve intestinal barrier function, and support the normal function of the immune system, providing health benefits to the host. Future studies should further investigate the antioxidant activity of vitamins on the gut microbiota and explore the causal relationships between vitamin regulation of the gut microbiota and host health.
FOOD RESEARCH INTERNATIONAL
(2023)
Review
Infectious Diseases
Giulia Patti, Carmen Pellegrino, Aurelia Ricciardi, Roberta Novara, Sergio Cotugno, Roberta Papagni, Giacomo Guido, Valentina Totaro, Giuseppina De Iaco, Federica Romanelli, Stefania Stolfa, Maria Letizia Minardi, Luigi Ronga, Ilenia Fato, Rossana Lattanzio, Davide Fiore Bavaro, Gina Gualano, Loredana Sarmati, Annalisa Saracino, Fabrizio Palmieri, Francesco Di Gennaro
Summary: Supplementation with multiple micronutrients, including zinc, may be more beneficial in TB compared to vitamin A alone. Vitamin C at high concentrations sterilizes drug-resistant TB cultures and prevents the emergence of drug persisters; Vitamin D suppresses mycobacterium replication in vitro, while VE shows a promising role in TB management due to its connection with oxidative balance.
Review
Fisheries
Abdel-Fattah M. El-Sayed, Marisol Izquierdo
Summary: Vitamin E plays a crucial role in farmed fish, providing antioxidant protection, improving immune response and growth performance, reducing muscle degeneration and atherosclerosis risk, enhancing reproductive efficiency and product quality. Consideration should be given to the interaction of VE with vitamin C and selenium, as well as lipid content in feed when supplementing VE.
REVIEWS IN AQUACULTURE
(2022)
Article
Nutrition & Dietetics
Min Cheol Chang, Sang Gyu Kwak, Soyoung Kwak
Summary: The meta-analysis found that high intake of vitamin E significantly reduced the risk of Parkinson's disease, while vitamin C intake did not show a significant protective effect. Further studies are needed to explore the exact mechanisms of vitamin E transportation and regulation in the central nervous system.
CLINICAL NUTRITION
(2021)
Review
Biochemistry & Molecular Biology
Liesa Regner-Nelke, Christopher Nelke, Christina B. Schroeter, Rainer Dziewas, Tobias Warnecke, Tobias Ruck, Sven G. Meuth
Summary: Vitamin E supplementation in neurodegenerative diseases shows inconsistent results, influenced by varying study designs and genetic variants. Recent studies suggest potential adverse effects of vitamin E supplementation on Alzheimer's disease, highlighting the need for cautious selection of suitable candidates for supplementation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Lianying Yao, Xiaoxiao Ma
Summary: This study empirically tests the impact of digital finance development on income distribution in China using statistical data from 280 prefectural-level cities. The results show a Kuznets effect of digital finance development on the income distribution of Chinese residents, with the income gap within regions continuing to increase. However, the positive effect of digital finance on income disparity weakens when regional economic development reaches a higher stage.
Review
Biotechnology & Applied Microbiology
Guangzheng Ma, Wenya Chong, Yuan Qi, Zeping Lu, Zihan Zhang, Binbin Nian, Yi Hu
Summary: Vitamin E (VE) is a natural antioxidant widely used in the food industry, but its easy oxidative inactivation and poor water solubility limit its application. Vitamin E esters' (VEEs) derivatives, such as vitamin E acetate (VEA), are more stable and easily absorbed with similar biological activities and physiological functions as VE. This systematic review summarizes the digestion, absorption, and physiological function of VEEs, as well as the synthesis strategies, particularly focusing on the use of ionic liquids (ILs) in enzymatic synthesis of VEEs. Future perspectives on developing more efficient strategies for VEEs synthesis, such as enzyme engineering and design of novel ILs, are also discussed.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2023)
Review
Oncology
Daoyan Wei, Liang Wang, Xiangsheng Zuo, Robert S. Bresalier
Summary: Pancreatic cancer has a poor prognosis and increasing incidence, necessitating novel intervention strategies. Vitamin D shows promise in reducing the risk and improving survival of pancreatic cancer, as well as regulating stromal reprogramming and immune response, providing opportunities for intervention.
Article
Biotechnology & Applied Microbiology
Anji Reddy Konda, Malleswari Gelli, Connor Pedersen, Rebecca E. Cahoon, Chunyu Zhang, Toshihiro Obata, Edgar B. Cahoon
Summary: The aim of this study was to increase tocochromanol production in camelina seeds by expressing target genes and enhancing biosynthesis. The results showed that co-expression of HPPD/TyrA and suppression of the HGO gene increased tocochromanol production by 2.5-fold and 1.4-fold, respectively.
METABOLIC ENGINEERING
(2023)
