WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity

Nicotinamide Mononucleotide Adenylyltransferase Is a Stress Response Protein Regulated by the Heat Shock Factor/Hypoxia-inducible Factor 1α Pathway

(2011) Yousuf O. Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Parkinsonian Mimetic, MPP+, Specifically Impairs Mitochondrial Transport in Dopamine Axons

(2011) J. S. Kim-Han et al.   JOURNAL OF NEUROSCIENCE

Axonal Degeneration Is Mediated by the Mitochondrial Permeability Transition Pore

(2011) S. A. Barrientos et al.   JOURNAL OF NEUROSCIENCE

6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

(2011) Alison I Bernstein et al.   Molecular Neurodegeneration

Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death

(2011) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical progression in Parkinson disease and the neurobiology of axons

(2010) Hsiao-Chun Cheng et al.   ANNALS OF NEUROLOGY

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Axonal Degeneration Is Blocked by Nicotinamide Mononucleotide Adenylyltransferase (Nmnat) Protein Transduction into Transected Axons

(2010) Yo Sasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration

(2010) Daniele Cartelli et al.   JOURNAL OF NEUROCHEMISTRY

Targeting NMNAT1 to Axons and Synapses Transforms Its Neuroprotective Potency In Vivo

(2010) E. Babetto et al.   JOURNAL OF NEUROSCIENCE

Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking†

(2009) Andreas Weihofen et al.   BIOCHEMISTRY

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

(2009) Rong Grace Zhai et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson’s disease

(2009) Teresa G. Hastings   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

WldSrequires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration

(2009) Michelle A. Avery et al.   JOURNAL OF CELL BIOLOGY

WldSprotein requires Nmnat activity and a short N-terminal sequence to protect axons in mice

(2009) Laura Conforti et al.   JOURNAL OF CELL BIOLOGY

Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

(2009) B. Beirowski et al.   JOURNAL OF NEUROSCIENCE

Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration

(2009) N. Yahata et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

A dual leucine kinase–dependent axon self-destruction program promotes Wallerian degeneration

(2009) Bradley R Miller et al.   NATURE NEUROSCIENCE

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity

(2009) Tingting Yan et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

Nmnat Delays Axonal Degeneration Caused by Mitochondrial and Oxidative Stress

(2008) C. Press et al.   JOURNAL OF NEUROSCIENCE

Dorsal Root Ganglion Neurons React to Semaphorin 3A Application through a Biphasic Response that Requires Multiple Myosin II Isoforms

(2008) Jacquelyn A. Brown et al.   MOLECULAR BIOLOGY OF THE CELL

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

(2008) R. Grace Zhai et al.   NATURE

Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds)

(2008) Thomas M Wishart et al.   GENOME BIOLOGY