Gintonin, a Ginseng-Derived Exogenous Lysophosphatidic Acid Receptor Ligand, Protects Astrocytes from Hypoxic and Re-oxygenation Stresses Through Stimulation of Astrocytic Glycogenolysis

Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly

(2018) Jangsup Moon et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Attenuates Alzheimer's Disease-Related Neuropathies: Involvement of Non-Amyloidogenic Processing

(2018) Sung Hee Hwang et al.   JOURNAL OF ALZHEIMERS DISEASE

The metabolic trinity, glucose–glycogen–lactate, links astrocytes and neurons in brain energetics, signaling, memory, and gene expression

(2017) Gerald A. Dienel   NEUROSCIENCE LETTERS

Hippocampus-dependent cognitive enhancement induced by systemic gintonin administration

(2016) Sungmin Kim et al.   Journal of Ginseng Research

Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP

(2015) J. Vogt et al.   EMBO Molecular Medicine

Lysophosphatidic Acid Signaling in the Nervous System

(2015) Yun C. Yung et al.   NEURON

Gintonin stimulates gliotransmitter release in cortical primary astrocytes

(2015) Hyunsook Kim et al.   NEUROSCIENCE LETTERS

Structure of ginseng major latex-like protein 151 and its proposed lysophosphatidic acid-binding mechanism

(2015) Sun-Hye Choi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Functional impact of glycogen degradation on astrocytic signalling: Figure 1

(2014) Margit S. Müller   BIOCHEMICAL SOCIETY TRANSACTIONS

Astrocytic glycogenolysis: mechanisms and functions

(2014) Leif Hertz et al.   METABOLIC BRAIN DISEASE

Molecular Basis of Impaired Glycogen Metabolism during Ischemic Stroke and Hypoxia

(2014) Mohammed Iqbal Hossain et al.   PLoS One

Sugar for the brain: the role of glucose in physiological and pathological brain function

(2013) Philipp Mergenthaler et al.   TRENDS IN NEUROSCIENCES

A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system

(2013) Hee Jin Kim et al.   Journal of Ginseng Research

Hippocampal c-Fos activation in normal and LPA1-null mice after two object recognition tasks with different memory demands

(2012) Estela Castilla-Ortega et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of Panax ginseng in Neurodegenerative Diseases

(2012) Ik-Hyun Cho   Journal of Ginseng Research

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Modulation of LPA Receptor Expression in the Human Brain Following Neurotrauma

(2011) Tony Frugier et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA1 Receptor Knockout Mice

(2011) Estela Castilla-Ortega et al.   PLoS One

Novel Glycolipoproteins from Ginseng

(2011) Mi-Kyung Pyo et al.   Journal of Ginseng Research

LPA Receptors: Subtypes and Biological Actions

(2010) Ji Woong Choi et al.   Annual Review of Pharmacology and Toxicology

LPA receptor expression in the central nervous system in health and following injury

(2010) Yona Goldshmit et al.   CELL AND TISSUE RESEARCH

Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor

(2010) Estela Castilla-Ortega et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling

(2009) Thorsten Trimbuch et al.   CELL

Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus

(2008) Elisa Matas-Rico et al.   MOLECULAR AND CELLULAR NEUROSCIENCE