The Neuronal Activity-Driven Transcriptome

Impaired Extinction of Learned Contextual Fear Memory in Early Growth Response 1 Knockout Mice

(2014) Seungrie Han et al.   MOLECULES AND CELLS

Decoding transcriptional repressor complexes in the adult central nervous system

(2014) Megumi Adachi et al.   NEUROPHARMACOLOGY

Significance of higher-order chromatin architecture for neuronal function and dysfunction

(2014) Grzegorz M. Wilczynski   NEUROPHARMACOLOGY

Transcriptional co-repressors and memory storage

(2014) Hannah Schoch et al.   NEUROPHARMACOLOGY

An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders

(2013) Steven Andrew Baker et al.   CELL

Matrix Metalloproteinase (MMP) 9 Transcription in Mouse Brain Induced by Fear Learning

(2013) Krishnendu Ganguly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Higher-Order Epigenetic Regulation of the Bdnf Gene upon Seizures

(2013) A. Walczak et al.   JOURNAL OF NEUROSCIENCE

Brain-Derived Neurotrophic Factor Induces Matrix Metalloproteinase 9 Expression in Neurons via the Serum Response Factor/c-Fos Pathway

(2013) B. Kuzniewska et al.   MOLECULAR AND CELLULAR BIOLOGY

The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition

(2013) Brenda L. Bloodgood et al.   NATURE

Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

(2013) Radosveta Koldamova et al.   NEUROBIOLOGY OF DISEASE

The Emerging Field of Neuroepigenetics

(2013) J. David Sweatt   NEURON

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

Splitting Hares and Tortoises: A classification of neuronal immediate early gene transcription based on poised RNA polymerase II

(2013) R.N. Saha et al.   NEUROSCIENCE

Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

(2013) Jose P. Lopez-Atalaya et al.   NUCLEIC ACIDS RESEARCH

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

(2013) Adam Lesiak et al.   PLoS One

Genome-Wide Profiling of the Activity-Dependent Hippocampal Transcriptome

(2013) Guido Hermey et al.   PLoS One

Binding of TFIIIC to SINE Elements Controls the Relocation of Activity-Dependent Neuronal Genes to Transcription Factories

(2013) Luca Crepaldi et al.   PLoS Genetics

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

Combinatorial complexity in chromatin structure and function: revisiting the histone code

(2012) Oliver J Rando   CURRENT OPINION IN GENETICS & DEVELOPMENT

NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors

(2012) Joshua D. Hawk et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum response factor modulates neuron survival during peripheral axon injury

(2012) Sina Stern et al.   Journal of Neuroinflammation

p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear

(2012) W. Wei et al.   JOURNAL OF NEUROSCIENCE

Differential roles for Nr4a1 and Nr4a2 in object location vs. object recognition long-term memory

(2012) S. E. McNulty et al.   LEARNING & MEMORY

Histone Regulation in the CNS: Basic Principles of Epigenetic Plasticity

(2012) Ian Maze et al.   NEUROPSYCHOPHARMACOLOGY

The adjustable nucleosome: an epigenetic signaling module

(2012) Bryan M. Turner   TRENDS IN GENETICS

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

OPERating ON Chromatin, a Colorful Language where Context Matters

(2011) Kathryn E. Gardner et al.   JOURNAL OF MOLECULAR BIOLOGY

cAMP Response Element-Binding Protein Is a Primary Hub of Activity-Driven Neuronal Gene Expression

(2011) E. Benito et al.   JOURNAL OF NEUROSCIENCE

Ablation of CBP in Forebrain Principal Neurons Causes Modest Memory and Transcriptional Defects and a Dramatic Reduction of Histone Acetylation But Does Not Affect Cell Viability

(2011) L. M. Valor et al.   JOURNAL OF NEUROSCIENCE

Genetic Approaches to Investigate the Role of CREB in Neuronal Plasticity and Memory

(2011) Angel Barco et al.   MOLECULAR NEUROBIOLOGY

Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II

(2011) Ramendra N Saha et al.   NATURE NEUROSCIENCE

What have we learned from gene expression profiles in Huntington's disease?

(2011) Tamara Seredenina et al.   NEUROBIOLOGY OF DISEASE

The Neuronal PAS Domain Protein 4 (Npas4) Is Required for New and Reactivated Fear Memories

(2011) Jonathan E. Ploski et al.   PLoS One

Npas4 Regulates a Transcriptional Program in CA3 Required for Contextual Memory Formation

(2011) K. Ramamoorthi et al.   SCIENCE

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Actin-mediated gene expression in neurons: the MRTF-SRF connection

(2010) Bernd Knöll   BIOLOGICAL CHEMISTRY

Ultrastructural and transcriptional profiling of neuropathological misregulation of CREB function

(2010) L M Valor et al.   CELL DEATH AND DIFFERENTIATION

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation

(2010) Lawryn H Kasper et al.   EMBO JOURNAL

Loss of the serum response factor in the dopamine system leads to hyperactivity

(2010) Jan Rodriguez Parkitna et al.   FASEB JOURNAL

Serum Response Factor Regulates Hippocampal Lamination and Dendrite Development and Is Connected with Reelin Signaling

(2010) C. Stritt et al.   MOLECULAR AND CELLULAR BIOLOGY

Microarray analysis of cultured rat hippocampal neurons treated with brain derived neurotrophic factor

(2010) Chiara Cazzin et al.   MOLECULAR BIOLOGY REPORTS

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

Transcriptome Analysis of the Hippocampal CA1 Pyramidal Cell Region after Kainic Acid-Induced Status Epilepticus in Juvenile Rats

(2010) Hanna B. Laurén et al.   PLoS One

CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

(2010) Eva Benito et al.   TRENDS IN NEUROSCIENCES

Temporal gene expression profile of the hippocampus following trace fear conditioning

(2009) Alessandra Sirri et al.   BRAIN RESEARCH

Adipocyte CREB Promotes Insulin Resistance in Obesity

(2009) Ling Qi et al.   Cell Metabolism

Inhibition of cAMP Response Element-Binding Protein Reduces Neuronal Excitability and Plasticity, and Triggers Neurodegeneration

(2009) Dragana Jancic et al.   CEREBRAL CORTEX

Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice

(2009) Kai Sun et al.   HEPATOLOGY

Identification of plasticity-associated genes regulated by Pavlovian fear conditioning in the lateral amygdala

(2009) Jonathan E. Ploski et al.   JOURNAL OF NEUROCHEMISTRY

Changes in the Proteome after NeuronalZif268Overexpression

(2009) Karsten Baumgärtel et al.   JOURNAL OF PROTEOME RESEARCH

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Neuroscience in the era of functional genomics and systems biology

(2009) Daniel H. Geschwind et al.   NATURE

Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression

(2009) Christine Stritt et al.   NATURE NEUROSCIENCE

The Function of Activity-Regulated Genes in the Nervous System

(2009) Sven Loebrich et al.   PHYSIOLOGICAL REVIEWS

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Functional versatility of transcription factors in the nervous system: the SRF paradigm

(2009) Bernd Knöll et al.   TRENDS IN NEUROSCIENCES

NF- B in the Nervous System

(2009) B. Kaltschmidt et al.   Cold Spring Harbor Perspectives in Biology

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Genome-wide investigation of in vivo EGR-1 binding sites in monocytic differentiation

(2009) Atsutaka Kubosaki et al.   GENOME BIOLOGY

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1

(2008) Akiko Hayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CREB has a context-dependent role in activity-regulated transcription and maintains neuronal cholesterol homeostasis

(2008) Thomas Lemberger et al.   FASEB JOURNAL

Kinase Networks Integrate Profiles ofN-Methyl-d-aspartate Receptor-mediated Gene Expression in Hippocampus

(2008) Marcelo P. Coba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Immediate Early Gene Arc/Arg3.1: Regulation, Mechanisms, and Function

(2008) C. R. Bramham et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent regulation of inhibitory synapse development by Npas4

(2008) Yingxi Lin et al.   NATURE

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

(2008) Suprabha Pulipparacharuvil et al.   NEURON

Target Identification for CNS Diseases by Transcriptional Profiling

(2008) C Anthony Altar et al.   NEUROPSYCHOPHARMACOLOGY

Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization

(2008) R.F. Paletzki et al.   NEUROSCIENCE

Rapid encoding of new information alters the profile of plasticity-related mRNA transcripts in the hippocampal CA3 region

(2008) R. P. Haberman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The impact of next-generation sequencing technology on genetics

(2008) Elaine R. Mardis   TRENDS IN GENETICS

Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip

(2008) Shilpi Arora et al.   GENOME BIOLOGY

Distinct functions of Egr gene family members in cognitive processes

(2008) Roseline Poirier   Frontiers in Neuroscience

CREB Binding and Activity in Brain: Regional Specificity and Induction by Electroconvulsive Seizure

(2007) Keith Quincy Tanis et al.   BIOLOGICAL PSYCHIATRY

LTP maintenance and its protein synthesis-dependence

(2007) Wickliffe C. Abraham et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The role of protein synthesis during the labile phases of memory: Revisiting the skepticism

(2007) Cristina M. Alberini   NEUROBIOLOGY OF LEARNING AND MEMORY