Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels

Genotype-Phenotype Relationships of Presenilin-1 Mutations in Alzheimer's Disease: An Update

(2017) Andrew J. Larner et al.   JOURNAL OF ALZHEIMERS DISEASE

Familial Alzheimer's disease sustained by presenilin 2 mutations: Systematic review of literature and genotype–phenotype correlation

(2014) Marco Canevelli et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction

(2013) Diana M. Sama et al.   AGEING RESEARCH REVIEWS

Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model

(2013) Katia Sesele et al.   AGING CELL

Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines

(2013) Andrew J. Payne et al.   EXPERIMENTAL NEUROLOGY

Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model

(2013) Simon Kaja et al.   VISION RESEARCH

Homer-1a immediate early gene expression correlates with better cognitive performance in aging

(2012) Simon Kaja et al.   AGE

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Lack of Evidence for Presenilins as Endoplasmic Reticulum Ca2+Leak Channels

(2012) Dustin Shilling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of calcium in synaptic plasticity and motor learning in the cerebellar cortex

(2012) Matthew G. Lamont et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity

(2012) Hui Wang et al.   NEURAL PLASTICITY

Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels

(2011) María-Ximena Silveyra et al.   NEUROBIOLOGY OF AGING

Sensing with the Motor Cortex

(2011) Nicholas G. Hatsopoulos et al.   NEURON

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice

(2010) I. Goussakov et al.   JOURNAL OF NEUROSCIENCE

γ-secretases: from cell biology to therapeutic strategies

(2010) Bruno A Bergmans et al.   LANCET NEUROLOGY

ER Calcium and Alzheimer's Disease: In a State of Flux

(2010) M. P. Mattson   Science Signaling

Presenilin transgenic mice as models of Alzheimer’s disease

(2009) Gregory A. Elder et al.   Brain Structure & Function

Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration

(2009) K. Tabuchi et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells

(2009) Akiko Oda et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Astrocytes going live: advances and challenges

(2009) Axel Nimmerjahn   JOURNAL OF PHYSIOLOGY-LONDON

The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein–protein interaction

(2008) Volodya Hayrapetyan et al.   CELL CALCIUM

The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity

(2007) Volodymyr Rybalchenko et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cellular distribution of γ-secretase subunit nicastrin in the developing and adult rat brains

(2007) A. Kodam et al.   NEUROBIOLOGY OF AGING

PS2 protein expression is upregulated by sex steroids in the cerebral cortex of aging mice

(2007) Soumi Ghosh et al.   NEUROCHEMISTRY INTERNATIONAL