MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia

TGF-  Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

(2014) B. C. Cooley et al.   Science Translational Medicine

Deficiency of MAPK-activated protein kinase 2 (MK2) prevents adverse remodelling and promotes endothelial healing after arterial injury

(2014) Piyushkumar Kapopara et al.   THROMBOSIS AND HAEMOSTASIS

Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo

(2013) Christopher E. Nelson et al.   ACS Nano

Ex Vivo Red Blood Cell Hemolysis Assay for the Evaluation of pH-responsive Endosomolytic Agents for Cytosolic Delivery of Biomacromolecular Drugs

(2013) Brian C. Evans et al.   Jove-Journal of Visualized Experiments

The cyclic AMP response element-binding protein (CREB) mediates smooth muscle cell proliferation in response to angiotensin II

(2013) Peter Molnar et al.   Journal of Cell Communication and Signaling

TLR 2 Induces Vascular Smooth Muscle Cell Migration Through cAMP Response Element−Binding Protein−Mediated Interleukin-6 Production

(2012) Guan-Lin Lee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cyclic adenosine monophosphate response-element binding protein activation by mitogen-activated protein kinase-activated protein kinase 3 and four-and-a-half LIM domains 5 plays a key role for vein graft intimal hyperplasia

(2012) Keisuke Nakanishi et al.   JOURNAL OF VASCULAR SURGERY

The Intracellular Pharmacokinetics of Terminally Capped Peptides

(2012) Ivo R. Ruttekolk et al.   MOLECULAR PHARMACEUTICS

Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo

(2011) Akihito Muto et al.   VASCULAR PHARMACOLOGY

Intracellular Delivery of a Protein Antigen with an Endosomal-Releasing Polymer Enhances CD8 T-Cell Production and Prophylactic Vaccine Efficacy

(2010) Suzanne Foster et al.   BIOCONJUGATE CHEMISTRY

Internalization and Intracellular Trafficking of a PTD-Conjugated Anti-Fibrotic Peptide, AZX100, in Human Dermal Keloid Fibroblasts

(2010) Charles R. Flynn et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model

(2010) Luciana B. Lopes et al.   JOURNAL OF VASCULAR SURGERY

Design of a bioactive cell-penetrating peptide: when a transduction domain does more than transduce

(2009) Brian Ward et al.   JOURNAL OF PEPTIDE SCIENCE

Role of heat shock protein 27 phosphorylation in migration of vascular smooth muscle cells

(2009) Hai-Feng Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer

(2009) Craig L. Duvall et al.   MOLECULAR PHARMACEUTICS

Development of a novel endosomolytic diblock copolymer for siRNA delivery

(2008) Anthony J. Convertine et al.   JOURNAL OF CONTROLLED RELEASE