A technology platform to assess multiple cancer agents simultaneously within a patient’s tumor

Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity

(2015) Biswanath Majumder et al.   Nature Communications

Prediction of individual response to anticancer therapy: historical and future perspectives

(2014) Florian T. Unger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Making Sure ADCs Don't Go Astray

(2014)   Cancer Discovery

Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues

(2013) Krupa J. Patel et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Drug Resistance: Challenges to Effective Therapy

(2012) M. P.V. Shekhar   CURRENT CANCER DRUG TARGETS

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities

(2012) Michele De Palma et al.   Molecular Oncology

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Impact of microdosing clinical study — Why necessary and how useful?

(2010) Yuichi Sugiyama et al.   ADVANCED DRUG DELIVERY REVIEWS

Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs

(2010) J A DiMasi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genetic bottlenecks and the hazardous game of population reduction in cell line based research

(2010) David Gisselsson et al.   EXPERIMENTAL CELL RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Antitumor Efficacy Testing in Rodents

(2008) Melinda G. Hollingshead   JNCI-Journal of the National Cancer Institute

Genomic Changes and Gene Expression Profiles Reveal That Established Glioma Cell Lines Are Poorly Representative of Primary Human Gliomas

(2008) A. Li et al.   MOLECULAR CANCER RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS