Role and Mechanism of Microglial Activation in Iron-Induced Selective and Progressive Dopaminergic Neurodegeneration

A delicate balance: Iron metabolism and diseases of the brain

(2013) Dominic Hare et al.   Frontiers in Aging Neuroscience

Functional roles of transferrin in the brain

(2011) Dominique F. Leitner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Enhanced Autophagy from Chronic Toxicity of Iron and Mutant A53T α-Synuclein

(2011) Katherine C. M. Chew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

(2011) Alison I Bernstein et al.   Molecular Neurodegeneration

Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity

(2010) Shannon Levesque et al.   BRAIN

Increased iron levels correlate with the selective nigral dopaminergic neuron degeneration in Parkinson’s disease

(2010) Zhanyun Lv et al.   JOURNAL OF NEURAL TRANSMISSION

Iron and reactive oxygen species activity in parkinsonian substantia nigra

(2010) Anna Wypijewska et al.   PARKINSONISM & RELATED DISORDERS

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

(2009) Ana G. Barbeito et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysaccharide administration

(2009) Bae Dong Jung et al.   NEUROCHEMISTRY INTERNATIONAL

Doxycycline is Neuroprotective Against Nigral Dopaminergic Degeneration by a Dual Mechanism Involving MMP-3

(2009) Yuri Cho et al.   NEUROTOXICITY RESEARCH

Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease

(2009) Wei Zhang et al.   NEUROTOXICITY RESEARCH

Neuroinflammation in the living brain of Parkinson's disease

(2009) Yasuomi Ouchi et al.   PARKINSONISM & RELATED DISORDERS

NADPH oxidase as a therapeutic target in Alzheimer's disease

(2008) Michelle L Block   BMC NEUROSCIENCE

The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery

(2008) Garima Dutta et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Dopamine complexes of iron in the etiology and pathogenesis of Parkinson’s disease

(2008) S ARREGUIN et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH

Dietary fats, cholesterol and iron as risk factors for Parkinson's disease

(2008) Karen M. Powers et al.   PARKINSONISM & RELATED DISORDERS

Proteome analysis of human substantia nigra in Parkinson's disease

(2008) Cornelius J Werner et al.   Proteome Science

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS